Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.
about
Etiology, triggers and neurochemical circuits associated with unexpected, expected, and laboratory-induced panic attacksHuman stiff-person syndrome IgG induces anxious behavior in ratsGABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop50 years of hurdles and hope in anxiolytic drug discoveryA role for LYNX2 in anxiety-related behavior.Activity-dependent regulation of inhibitory synapse development by Npas4Metabolomic analysis of anti-hypoxia and anti-anxiety effects of Fu Fang Jin Jing Oral LiquidIncreased anxiety-like behavior and enhanced synaptic efficacy in the amygdala of GluR5 knockout miceLoss of MeCP2 in Parvalbumin-and Somatostatin-Expressing Neurons in Mice Leads to Distinct Rett Syndrome-like PhenotypesCritical period for acoustic preference in mice.Reduced glutamate decarboxylase 65 protein within primary auditory cortex inhibitory boutons in schizophrenia.The impact of adult vitamin D deficiency on behaviour and brain function in male Sprague-Dawley ratsThe age of anxiety: role of animal models of anxiolytic action in drug discovery.Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations.The clinical implications of mouse models of enhanced anxiety.Critical role of the 65-kDa isoform of glutamic acid decarboxylase in consolidation and generalization of Pavlovian fear memoryDeletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.Structural and functional analysis of cysteine residues in human glutamate decarboxylase 65 (GAD65) and GAD67.The missing piece in the 'use it or lose it' puzzle: is inhibition regulated by activity or does it act on its own accord?Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice.Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence.Glutamic acid decarboxylase 65: a link between GABAergic synaptic plasticity in the lateral amygdala and conditioned fear generalizationGenetic association analysis of behavioral inhibition using candidate loci from mouse models.GAD65 haplodeficiency conveys resilience in animal models of stress-induced psychopathologyEmbryonic GABA(B) receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice.Two distinct mechanisms target GAD67 to vesicular pathways and presynaptic clustersMurine GRPR and stathmin control in opposite directions both cued fear extinction and neural activities of the amygdala and prefrontal cortex.Demonstration of functional coupling between gamma -aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesiclesCalpain cleavage of brain glutamic acid decarboxylase 65 is pathological and impairs GABA neurotransmission.Molecular mechanisms of neurotransmitter release.Mice lacking Gad2 show altered behavioral effects of ethanol, flurazepam and gabaxadol.Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias.Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.Altered GABA transmission in a mouse model of increased trait anxietyNF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity.Tonic excitation or inhibition is set by GABA(A) conductance in hippocampal interneurons.Alcohol alters the activation of ERK1/2, a functional regulator of binge alcohol drinking in adult C57BL/6J mice.Long-term behavioral programming induced by peripuberty stress in rats is accompanied by GABAergic-related alterations in the Amygdala.Specific phobia is a frequent non-motor feature in stiff man syndromeCompartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neurons
P2860
Q27026213-3956D9A5-5025-4F77-AFDA-F386B3F823F8Q27437613-0AD1E3C4-7053-4A36-B0D5-74DC8C339FC1Q27644229-481B2929-2B94-43E1-94FD-6C53D3C36EA5Q28297569-A75CD2DD-8B95-448D-8378-A8C6B2108C7FQ28507664-0EFC130D-E604-4407-8DB1-12EBD40AB3E3Q28510423-A399D1B3-24A1-42FF-9A7C-4ED41843D650Q28534520-70BEBC37-05BF-4C86-B370-72D49C36B3CCQ28586201-9AF090EF-3ECC-4CCA-A8FD-6F98E1A179CFQ30369619-6761AB75-605B-499E-9F13-667A7E059884Q30422042-FED16A9D-BF87-4E7B-BB45-8D157E7860ECQ30447651-EC4322B0-4984-416C-8975-64D8BC9A14FBQ30450779-07E35859-A7B1-4954-B197-86253AB5EC0EQ30462832-0EBA9C35-EA65-462F-8F50-4040C86D86ABQ30474166-41DDAEE6-6A1A-4ADE-98F7-61153E05BB16Q30474232-B516BCEE-2963-4F44-8D6C-369A925D8D34Q30490998-5D6D75F2-CCF2-41F1-9196-A3F262BCDD42Q30529898-7FA20705-27AA-4E91-BAEB-4D570AD19D8DQ31160750-82575884-A892-419F-9236-0AFC0BF2FEF3Q33344846-A6C7D27C-E26D-4AF0-AC29-B2FF2C2A9C0EQ33545249-6B4EED32-A424-427F-B438-B8E3D609F370Q33750970-F1DB2606-1D8B-4005-88F6-365C954CAF06Q33923646-674C0FAD-966A-4C97-8556-F345D0FE5818Q33946742-33F50BC9-1F46-45AE-A6D0-254709925E4CQ34013738-7CDCFCC1-B249-4047-9EBF-EE156780CAF3Q34097713-5EDE22F5-7CDF-4AD0-AAAF-8052BDC7AAA4Q34111028-E8C925DF-09D1-483D-A4EF-E9A1DBF3C6FAQ34152671-D525F0F6-F0F6-4DD4-8075-DDDBFB0BBC08Q34183366-C38011CB-90C4-437D-885F-1B8D0BF5737AQ34200288-5B78DF25-2243-4739-BC56-A176F63F99E2Q34228641-FE10AD61-4D96-4516-A013-14C438DACD28Q34572122-A1721D8B-7023-4695-AEFB-0AEB67B5B05EQ34669020-712CA51A-40A6-46E8-B501-E15624B55782Q34798306-14363CC9-0998-4B66-BB1A-B624418944C1Q34976116-1CFF65DA-D9E1-4FD1-8A89-EEB97607A7B0Q35071293-DDD41BDE-B677-4610-B27C-6A87BC3D2877Q35130705-D818E1F7-6EC8-4B16-8F85-E874F5EEF697Q35142862-FE2C3405-2878-4AC3-B634-0FCD717F8863Q35148944-4875A83F-84ED-4B58-8F7E-D98F1CD8A927Q35472637-330C2360-E8D3-4AD1-8800-71EE81F999B0Q35554433-784A22C3-53AA-400E-8247-9A589E6694DB
P2860
Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Increased anxiety and altered ...... f glutamic acid decarboxylase.
@ast
Increased anxiety and altered ...... f glutamic acid decarboxylase.
@en
type
label
Increased anxiety and altered ...... f glutamic acid decarboxylase.
@ast
Increased anxiety and altered ...... f glutamic acid decarboxylase.
@en
prefLabel
Increased anxiety and altered ...... f glutamic acid decarboxylase.
@ast
Increased anxiety and altered ...... f glutamic acid decarboxylase.
@en
P2860
P356
P1476
Increased anxiety and altered ...... of glutamic acid decarboxylase
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.4.1698
P407
P577
1999-02-01T00:00:00Z