6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells.
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Indirubin and Indirubin Derivatives for Counteracting Proliferative DiseasesAre the Traditional Medical Uses of Muricidae Molluscs Substantiated by Their Pharmacological Properties and Bioactive Compounds?Spirooxindole derivative SOID-8 induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cellsProteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cellsRole of STAT3 in cancer metastasis and translational advances.Low-dose 6-bromoindirubin-3'-oxime induces partial dedifferentiation of endothelial cells to promote increased neovascularization.Regulation and function of signal transducer and activator of transcription 3.6-Bromoindirubin-3'oxime (BIO) decreases proliferation and migration of canine melanoma cell lines.GSK3 inhibitors CHIR99021 and 6-bromoindirubin-3'-oxime inhibit microRNA maturation in mouse embryonic stem cellsGlucose-6-phosphate dehydrogenase and NADPH oxidase 4 control STAT3 activity in melanoma cells through a pathway involving reactive oxygen species, c-SRC and SHP2.A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signalingInhibition of the STAT3 signaling pathway contributes to apigenin-mediated anti-metastatic effect in melanoma.MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cellsIn vivo animal models for studying brain metastasis: value and limitations.Targets, structures, and recent approaches in malignant melanoma chemotherapy.Selective JAK inhibitors.Indirubin derivatives: a patent review (2010 - present).Suppression of the Growth and Invasion of Human Head and Neck Squamous Cell Carcinomas via Regulating STAT3 Signaling and the miR-21/β-catenin Axis with HJC0152.6BIO Enhances Oligonucleotide Activity in Cells: A Potential Combinatorial Anti-androgen Receptor Therapy in Prostate Cancer Cells.Effects of the GSK-3β inhibitor (2Z,3E)-6-bromoindirubin-3'-oxime upon ovarian cancer cells.Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling.Suppressor of cytokine signalling-1 induces significant preclinical antitumor effect in malignant melanoma cells.Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling.Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells.Design, Synthesis, and Antitumor Evaluation of 4-Amino-(1H)-pyrazole Derivatives as JAKs InhibitorsInduction of atypical cell death in thyroid carcinoma cells by the indirubin derivative 7-bromoindirubin-3'-oxime (7BIO).GSK-3β Inhibition Induced Neuroprotection, Regeneration, and Functional Recovery After Intracerebral Hemorrhagic Stroke.Stattic Enhances Radiosensitivity and Reduces Radio-Induced Migration and Invasion in HCC Cell Lines through an Apoptosis Pathway.Nitidine chloride acts as an apoptosis inducer in human oral cancer cells and a nude mouse xenograft model via inhibition of STAT3.MCL1 is deregulated in subgroups of diffuse large B-cell lymphoma.
P2860
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P2860
6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
6-Bromoindirubin-3'-oxime inhi ...... tosis of human melanoma cells.
@ast
6-Bromoindirubin-3'-oxime inhi ...... tosis of human melanoma cells.
@en
type
label
6-Bromoindirubin-3'-oxime inhi ...... tosis of human melanoma cells.
@ast
6-Bromoindirubin-3'-oxime inhi ...... tosis of human melanoma cells.
@en
prefLabel
6-Bromoindirubin-3'-oxime inhi ...... tosis of human melanoma cells.
@ast
6-Bromoindirubin-3'-oxime inhi ...... tosis of human melanoma cells.
@en
P2093
P2860
P1433
P1476
6-Bromoindirubin-3'-oxime inhi ...... ptosis of human melanoma cells
@en
P2093
Anna Scuto
Leandros Skaltsounis
Panos Polychronopoulos
Richard Jove
Sangkil Nam
P2860
P304
P356
10.1158/0008-5472.CAN-10-3852
P407
P577
2011-05-24T00:00:00Z