Prdm16 is a physiologic regulator of hematopoietic stem cells. - Wikidata - awgldk - TriplyDB

Prdm16 is a physiologic regulator of hematopoietic stem cells.

Prdm16 is a physiologic regulator of hematopoietic stem cells.

http://www.wikidata.org/entity/Q35029415

about

The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo Adaptive admixture in the West African bovine hybrid zone: insight from the Borgou population.Metabolic regulation of stem cell function.Downregulation of Prdm16 mRNA is a specific antileukemic mechanism during HOXB4-mediated HSC expansion in vivo.Pathogenic microRNA's in myeloid malignancies.Quantitative trait mapping reveals a regulatory axis involving peroxisome proliferator-activated receptors, PRDM16, transforming growth factor-β2 and FLT3 in hematopoiesis SUMOylation of sPRDM16 promotes the progression of acute myeloid leukemia.Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome.Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress.miR-101 reverses hypomethylation of the PRDM16 promoter to disrupt mitochondrial function in astrocytoma cells PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.Delineating the mixed lineage leukemia gene expression network in hematopoietic stem cells.An MLL-dependent network sustains hematopoiesis.Medial HOXA genes demarcate haematopoietic stem cell fate during human development.Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells.Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential.Identification of Hematopoietic Stem Cell Engraftment Genes in Gene Therapy Studies.Mapping Whole-Transcriptome Splicing in Mouse Hematopoietic Stem Cells.SET for life: biochemical activities and biological functions of SET domain-containing proteins Stem cells, redox signaling, and stem cell aging.Concise review: managing genotoxicity in the therapeutic modification of stem cells.PRDM proteins: important players in differentiation and disease.High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML.ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells.Reprogrammed chondrocytes engineered to produce IL-12 provide novel ex vivo immune-gene therapy for cancer.Genome-wide methylation analysis identifies novel CpG loci for perimembranous ventricular septal defects in human.Generation of a multipurpose Prdm16 mouse allele by targeted gene trapping PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing.Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells.DNA hypermethylation of CD3(+) T cells from cord blood of infants exposed to intrauterine growth restriction.DNA methylation in PRDM8 is indicative for dyskeratosis congenita.PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity.PRDM16 (1p36) translocations define a distinct entity of myeloid malignancies with poor prognosis but may also occur in lymphoid malignancies.The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina.The transcriptional landscape of hematopoietic stem cell ontogeny The subtype-specific features of EVI1 and PRDM16 in acute myeloid leukemia.NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia.Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells.Glutathione peroxidases as oncotargets.Clinical features and prognostic impact of PRDM16 expression in adult acute myeloid leukemia.

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Prdm16 is a physiologic regulator of hematopoietic stem cells.

http://www.wikidata.org/entity/Q35029415

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2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Prdm16 is a physiologic regulator of hematopoietic stem cells.

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Prdm16 is a physiologic regulator of hematopoietic stem cells.

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type

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Prdm16 is a physiologic regulator of hematopoietic stem cells.

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Prdm16 is a physiologic regulator of hematopoietic stem cells.

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Prdm16 is a physiologic regulator of hematopoietic stem cells.

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Prdm16 is a physiologic regulator of hematopoietic stem cells.

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Prdm16 is a physiologic regulator of hematopoietic stem cells

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P2093

Amy Labar

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Betty Y Zhou

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Hans-Willem Snoeck

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Ihor R Lemischka

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Parameet Kumar

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Serine Avagyan

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P2860

A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex

PRDM16 controls a brown fat/skeletal muscle switch

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

A functional screen to identify novel effectors of hematopoietic stem cell activity

Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention

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19

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117

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Francesca Aguilo

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2011-02-22T00:00:00Z

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49857199

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21343612

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3109532

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