Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist. - Wikidata - awgldk - TriplyDB

Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.

Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.

http://www.wikidata.org/entity/Q35042314

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LP-211 is a brain penetrant selective agonist for the serotonin 5-HT(7) receptor Serotonin 5-HT7 receptor agents: Structure-activity relationships and potential therapeutic applications in central nervous system disorders SB-656104-A, a novel selective 5-HT7 receptor antagonist, modulates REM sleep in rats Targeting the Serotonin 5-HT7 Receptor in the Search for Treatments for CNS Disorders: Rationale and Progress to Date [(3)H]-SB-269970--A selective antagonist radioligand for 5-HT(7) receptors The effect of SB-269970, a 5-HT(7) receptor antagonist, on 5-HT release from serotonergic terminals and cell bodies Characterization of the receptors involved in the 5-HT-induced excitation of canine antral longitudinal muscle Effects of the selective 5-HT7 receptor antagonist SB-269970 and amisulpride on ketamine-induced schizophrenia-like deficits in rats.Evidence for the involvement of central 5-HT7 receptors in the micturition reflex in anaesthetized female rats Inactivation of the 5-HT(7) receptor partially blocks phencyclidine-induced disruption of prepulse inhibition.Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol Functional interactions between 5-HT2A and presynaptic 5-HT1A receptor-based responses in mice genetically deficient in the serotonin 5-HT transporter (SERT)The 5-HT(7) receptor as a mediator and modulator of antidepressant-like behavior.How (and why) the immune system makes us sleep.The 5-HT7 receptor and disorders of the nervous system: an overview.Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission 5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders.Role of the 5-HT7 receptor in the central nervous system: from current status to future perspectives.5-HT(1A) and 5-HT(7) receptors differently modulate AMPA receptor-mediated hippocampal synaptic transmission.No hypothermic response to serotonin in 5-HT7 receptor knockout mice.Interplay between serotonin 5-HT1A and 5-HT7 receptors in depressive disorders.Therapeutic potential of serotonin antagonists in depressive disorders.Pharmacological characterization of the 5-HT receptors mediating contraction and relaxation of canine isolated proximal stomach smooth muscle.5-HT7 receptors mediate the inhibitory effect of 5-HT on peristalsis in the isolated guinea-pig ileum Autoradiographic distribution of 5-HT7 receptors in the human brain using [3H]mesulergine: comparison to other mammalian species.Effect of 5-HT7 receptor blockade on liver regeneration after 60-70% partial hepatectomy.The role of central 5-hydroxytryptamine (5-HT, serotonin) receptors in the control of micturition.The 5-HT(7) receptor in learning and memory.Expression of 5-HT7 receptor mRNA in the hamster brain: effect of aging and association with calbindin-D28K expression.5-HT7 receptor modulates GABAergic transmission in the rat dorsal raphe nucleus and controls cortical release of serotonin Vagal control of the heart: central serotonergic (5-HT) mechanisms.Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice Assessing the neuronal serotonergic target-based antidepressant stratagem: impact of in vivo interaction studies and knockout models Synaptic transmission at functionally identified synapses in the enteric nervous system: roles for both ionotropic and metabotropic receptors.Hippocampal serotonin-1A receptor function in a mouse model of anxiety induced by long-term voluntary wheel running.Building a better antipsychotic: receptor targets for the treatment of multiple symptom dimensions of schizophrenia.Peripheral and spinal 5-HT receptors participate in cholestatic itch and antinociception induced by bile duct ligation in rats.Human 5-HT(4) and 5-HT(7) receptor splice variants: are they important?5-HT(7) receptor modulators: a medicinal chemistry survey of recent patent literature (2004 - 2009).The 5-HT7 receptor as a potential target for treating drug and alcohol abuse.

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P2860

Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.

http://www.wikidata.org/entity/Q35042314

description

2000 nî lūn-bûn

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2000 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հունիսին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.

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Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.

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Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.

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Characterization of SB-269970-A, a selective 5-HT(7) receptor antagonist.

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A D Medhurst

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P2860

Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase

Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation

5-CT stimulation of adenylyl cyclase activity in guinea-pig hippocampus: evidence for involvement of 5-HT7 and 5-HT1A receptors

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)

Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719

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Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype

Human serotonin 5-HT7 receptor: cloning and pharmacological characterisation of two receptor variants

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