The NOP (ORL1) receptor antagonist Compound B stimulates mesolimbic dopamine release and is rewarding in mice by a non-NOP-receptor-mediated mechanism.
about
The Nociceptin Receptor as an Emerging Molecular Target for Cocaine AddictionThe pharmacology of Ro 64-6198, a systemically active, nonpeptide NOP receptor (opiate receptor-like 1, ORL-1) agonist with diverse preclinical therapeutic activity.The endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine.Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced parkinsonism.Nociceptin Opioid Receptor (NOP) as a Therapeutic Target: Progress in Translation from Preclinical Research to Clinical Utility.Social defeat disrupts reward learning and potentiates striatal nociceptin/orphanin FQ mRNA in rats.A systematic review of the role of the nociceptin receptor system in stress, cognition, and reward: relevance to schizophrenia.Endogenous nociceptin (orphanin FQ) suppresses basal hedonic state and acute reward responses to methamphetamine and ethanol, but facilitates chronic responses.
P2860
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P2860
The NOP (ORL1) receptor antagonist Compound B stimulates mesolimbic dopamine release and is rewarding in mice by a non-NOP-receptor-mediated mechanism.
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The NOP (ORL1) receptor antago ...... P-receptor-mediated mechanism.
@en
type
label
The NOP (ORL1) receptor antago ...... P-receptor-mediated mechanism.
@en
prefLabel
The NOP (ORL1) receptor antago ...... P-receptor-mediated mechanism.
@en
P2093
P2860
P356
P1476
The NOP (ORL1) receptor antago ...... P-receptor-mediated mechanism.
@en
P2093
Kazuto Sakoori
Miwako Koizumi
Naoko Midorikawa
Niall P Murphy
P2860
P356
10.1038/SJ.BJP.0705906
P407
P577
2004-08-02T00:00:00Z