Design, creation, and characterization of a stable, monomeric triosephosphate isomerase. - Wikidata - awgldk - TriplyDB

Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

http://www.wikidata.org/entity/Q35055478

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Perturbation of the Dimer Interface of Triosephosphate Isomerase and its Effect on Trypanosoma cruzi Revisiting the mechanism of the triosephosphate isomerase reaction: the role of the fully conserved glutamic acid 97 residue Probing the role of highly conserved residues in triosephosphate isomerase--analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzyme When monomers are preferred: a strategy for the identification and disruption of weakly oligomerized proteins Reflections on the catalytic power of a TIM-barrel.Identification of fibrillogenic regions in human triosephosphate isomerase.Computer simulation of the triosephosphate isomerase catalyzed reaction.Investigating and Engineering Enzymes by Genetic Selection.Wildtype and engineered monomeric triosephosphate isomerase from Trypanosoma brucei: partitioning of reaction intermediates in D2O and activation by phosphite dianion.The loop opening/closing motion of the enzyme triosephosphate isomerase Substrate-Induced Dimerization of Engineered Monomeric Variants of Triosephosphate Isomerase from Trichomonas vaginalis.Engineering subunit association of multisubunit proteins: a dimeric streptavidin.Identification of the Serratia endonuclease dimer: structural basis and implications for catalysis.The role of quaternary interactions on the stability and activity of ascorbate peroxidase Disruption of the aldolase A tetramer into catalytically active monomers A paradigm for enzyme-catalyzed proton transfer at carbon: triosephosphate isomerase.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Structural basis for the biological activities of bovine seminal ribonuclease.Computer applications for prediction of protein-protein interactions and rational drug design.A guide to the effects of a large portion of the residues of triosephosphate isomerase on catalysis, stability, druggability, and human disease.Crystal structures of two monomeric triosephosphate isomerase variants identified via a directed-evolution protocol selecting for L-arabinose isomerase activity.Conformational stability of dimeric proteins: quantitative studies by equilibrium denaturation.Thermodynamic characterization of yeast triosephosphate isomerase refolding: insights into the interplay between function and stability as reasons for the oligomeric nature of the enzyme.Active site properties of monomeric triosephosphate isomerase (monoTIM) as deduced from mutational and structural studies.Dissection of the gene of the bifunctional PGK-TIM fusion protein from the hyperthermophilic bacterium Thermotoga maritima: design and characterization of the separate triosephosphate isomerase Mass spectrometric identification of an intramolecular disulfide bond in thermally inactivated triosephosphate isomerase from a thermophilic organism Methanocaldococcus jannaschii.Characterization of a monomeric Escherichia coli alkaline phosphatase formed upon a single amino acid substitution.Thermodynamic analysis of the dissociation of the aldolase tetramer substituted at one or both of the subunit interfaces.Role of an N-terminal extension in stability and catalytic activity of a hyperthermostable α/β hydrolase fold esterase.Detection of the protein dimers, multiple monomeric states and hydrated forms of Plasmodium falciparum triosephosphate isomerase in the gas phase.Structure-based directed evolution of a monomeric triosephosphate isomerase: toward a pentose sugar isomerase.Redesigning the Quaternary Structure of R67 Dihydrofolate Reductase

P2860

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P2860

Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

http://www.wikidata.org/entity/Q35055478

description

1994 nî lūn-bûn

@nan

1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

1994 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

1994年の論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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1994年论文

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name

Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

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Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

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type

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Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

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Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

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prefLabel

Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

@ast

Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Design, creation, and characterization of a stable, monomeric triosephosphate isomerase.

@en

P2093

Abagyan R

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Borchert TV

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Jaenicke R

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Wierenga RK

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P2860

A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

Atomic solvation parameters applied to molecular dynamics of proteins in solution

Refined 1.83 A structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 M-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

Kinetic properties of triose-phosphate isomerase from Trypanosoma brucei brucei. A comparison with the rabbit muscle and yeast enzymes

Replacing the (beta alpha)-unit 8 of E.coli TIM with its chicken homologue leads to a stable and active hybrid enzyme.

The evolution of alpha/beta barrel enzymes.

Probing the catalytic sites of triosephosphate isomerase by 31P-NMR with reversibly and irreversibly binding substrate analogues.

Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface.

The codon preference plot: graphic analysis of protein coding sequences and prediction of gene expression.

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1515-1518

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scholarly article

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10.1073/PNAS.91.4.1515

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4

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91

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8108439

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43190

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