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Inhibition of acyl-coenzyme A:cholesterol acyltransferase stimulates cholesterol efflux from macrophages and stimulates farnesoid X receptor in hepatocytesPhytochemicals as novel agents for the induction of browning in white adipose tissueTargeting beta-catenin signaling to induce apoptosis in human breast cancer cells by z-guggulsterone and Gugulipid extract of Ayurvedic medicine plant Commiphora mukul.Simultaneous estimation of E- and Z-isomers of guggulsterone in rabbit plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study.Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cellsThe hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: dominance of transactivation over farsenoid X receptor-mediated antagonismIdentification of trisubstituted-pyrazol carboxamide analogs as novel and potent antagonists of farnesoid X receptor.Prevention of endotoxin-induced uveitis in rats by plant sterol guggulsteroneEvidence of lifestyle modification in the management of hypercholesterolemia.Protective effect of guggulsterone against cardiomyocyte injury induced by doxorubicin in vitroDeciphering the nuclear bile acid receptor FXR paradigm.Reactive oxygen species-dependent apoptosis by gugulipid extract of Ayurvedic medicine plant Commiphora mukul in human prostate cancer cells is regulated by c-Jun N-terminal kinase.Development of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discoveryInhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma.Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approachHypolipidemic agent Z-guggulsterone: metabolism interplays with induction of carboxylesterase and bile salt export pumpGuggulsterone inhibits human cholangiocarcinoma Sk-ChA-1 and Mz-ChA-1 cell growth by inducing caspase-dependent apoptosis and downregulation of survivin and Bcl-2 expression.Analgesic, anti-inflammatory and anti-hyperlipidemic activities of Commiphora molmol extract (Myrrh).Pharmacology and Phytochemistry of Oleo-Gum Resin of Commiphora wightii (Guggulu)From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer.Ayurvedic medicinal plants for Alzheimer's disease: a review.Inhibition of farnesoid X receptor controls esophageal cancer cell growth in vitro and in nude mouse xenografts.Therapeutic effects of guggul and its constituent guggulsterone: cardiovascular benefits.Review article: cytochrome P450 enzyme, and transport protein mediated herb-drug interactions in renal transplant patients: grapefruit juice, St John's Wort - and beyond!Guggulsterone modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in SENCAR mice.Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products.Activation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) by herbal medicines.Protective effect of ethanolic extract of Commiphora mukul gum resin against oxidative stress in the brain of streptozotocin induced diabetic Wistar male rats.Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3Potential therapeutic targets of Guggulsterone in cancerOvercoming multidrug resistance in human cancer cells by natural compoundsGuggulsterone Attenuated Lipopolysaccharide-Induced Inflammatory Responses in Mouse Inner Medullary Collecting Duct-3 Cells.Commiphora mukul attenuates peripheral neuropathic pain induced by chronic constriction injury of sciatic nerve in rats.The guggulsterone derivative GG-52 inhibits NF-κB signaling in gastric epithelial cells and ameliorates ethanol-induced gastric mucosal lesions in mice.Reversal of multidrug resistance by guggulsterone in drug-resistant MCF-7 cell lines.Novel guggulsterone derivative GG-52 inhibits NF-kappaB signaling in intestinal epithelial cells and attenuates acute murine colitis.Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis.Gugulipid causes hypercholesterolemia leading to endothelial dysfunction, increased atherosclerosis, and premature death by ischemic heart disease in male mice.Per os colchicine administration in cholesterol fed rabbits: Triglycerides lowering effects without affecting atherosclerosis progress.Z-Guggulsterone Produces Antidepressant-Like Effects in Mice through Activation of the BDNF Signaling Pathway.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
GUGULIPID: a natural cholesterol-lowering agent.
@ast
GUGULIPID: a natural cholesterol-lowering agent.
@en
type
label
GUGULIPID: a natural cholesterol-lowering agent.
@ast
GUGULIPID: a natural cholesterol-lowering agent.
@en
prefLabel
GUGULIPID: a natural cholesterol-lowering agent.
@ast
GUGULIPID: a natural cholesterol-lowering agent.
@en
P1476
GUGULIPID: a natural cholesterol-lowering agent.
@en
P2093
David D Moore
Nancy L Urizar
P304
P356
10.1146/ANNUREV.NUTR.23.011702.073102
P407
P577
2003-02-26T00:00:00Z