Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3
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HCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell linesMolecular targets for anticancer redox chemotherapy and cisplatin-induced ototoxicity: the role of curcumin on pSTAT3 and Nrf-2 signalling.High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines.Targeting beta-catenin signaling to induce apoptosis in human breast cancer cells by z-guggulsterone and Gugulipid extract of Ayurvedic medicine plant Commiphora mukul.Association of FGFR2 rs2981582, SIRT1 rs12778366, STAT3 rs744166 gene polymorphisms with pituitary adenoma.14-3-3 zeta is a molecular target in guggulsterone induced apoptosis in head and neck cancer cells.Simultaneous estimation of E- and Z-isomers of guggulsterone in rabbit plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study.Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cellsHonokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors.Suppression of STAT3 and HIF-1 alpha mediates anti-angiogenic activity of betulinic acid in hypoxic PC-3 prostate cancer cells.Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathwayExpression of AFP and STAT3 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in AFP-producing gastric cancer cellsAh receptor antagonism inhibits constitutive and cytokine inducible IL6 production in head and neck tumor cell lines.Reactive oxygen species-dependent apoptosis by gugulipid extract of Ayurvedic medicine plant Commiphora mukul in human prostate cancer cells is regulated by c-Jun N-terminal kinase.STAT3 signaling: anticancer strategies and challenges.Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma.Receptor-tyrosine-kinase-targeted therapies for head and neck cancer.Induction of BCL2-Interacting Killer, BIK, is Mediated for Anti-Cancer Activity of Curcumin in Human Head and Neck Squamous Cell Carcinoma Cells.Suppression of the pregnane X receptor during endoplasmic reticulum stress is achieved by down-regulating hepatocyte nuclear factor-4α and up-regulating liver-enriched inhibitory protein.Dual kinase inhibition of EGFR and HER2 overcomes resistance to cetuximab in a novel in vivo model of acquired cetuximab resistance.Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide.Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling.Potential therapeutic targets of Guggulsterone in cancerInvestigational EGFR-targeted therapy in head and neck squamous cell carcinoma.Pharmacotherapy for squamous-cell carcinoma of the head and neck.Anti-epidermal growth factor receptor therapy in head and neck squamous cell carcinoma: focus on potential molecular mechanisms of drug resistanceSTAT3-Mediated Metabolic Reprograming in Cellular Transformation and Implications for Drug ResistanceIntegration of phytochemicals and phytotherapy into cancer precision medicine.Guggulsterone and Its Role in Chronic Diseases.SERPINB2 down-regulation contributes to chemoresistance in head and neck cancer.Sensitization of head and neck cancer to cisplatin through the use of a novel curcumin analog.A novel synthetic Asiatic acid derivative induces apoptosis and inhibits proliferation and mobility of gastric cancer cells by suppressing STAT3 signaling pathway.Guggulsterone induces apoptosis of human hepatocellular carcinoma cells through intrinsic mitochondrial pathway.Over-expression of BAG-1 in head and neck squamous cell carcinomas (HNSCC) is associated with cisplatin-resistance.Development and Validation of RP-HPLC Method for Simultaneous Estimation of Picroside I, Plumbagin, and Z-guggulsterone in Tablet Formulation.High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines.A Review of Promising Natural Chemopreventive Agents for Head and Neck Cancer.Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases
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Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 September 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Guggulsterone enhances head an ...... d activator of transcription-3
@en
Guggulsterone enhances head an ...... activator of transcription-3.
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type
label
Guggulsterone enhances head an ...... d activator of transcription-3
@en
Guggulsterone enhances head an ...... activator of transcription-3.
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prefLabel
Guggulsterone enhances head an ...... d activator of transcription-3
@en
Guggulsterone enhances head an ...... activator of transcription-3.
@nl
P2093
P2860
P50
P356
P1433
P1476
Guggulsterone enhances head an ...... d activator of transcription-3
@en
P2093
Changyou Li
Daniel E Johnson
Eun-Ryeong Hahm
Maria L Freilino
Mary C Panahandeh
Raja R Seethala
Rebecca J Leeman-Neill
Shivendra V Singh
Sonali C Joyce
P2860
P304
P356
10.1093/CARCIN/BGP211
P407
P577
2009-09-16T00:00:00Z