Baseline lipophilicity relationships in human cytochromes P450 associated with drug metabolism.

Baseline lipophilicity relationships in human cytochromes P450 associated with drug metabolism.

Item
http://www.wikidata.org/entity/Q35085025
Calibration of the channel that determines the omega-hydroxylation regiospecificity of cytochrome P4504A1: catalytic oxidation of 12-HALODOdecanoic acids.Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity.Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates.Lipophilicity in drug discovery.The Cytochrome P450 3A4 Has Three Major Conformations: New Clues to Drug Recognition by this Promiscuous Enzyme.Quantitative Property-Property Relationship for Screening-Level Prediction of Intrinsic Clearance of Volatile Organic Chemicals in Rats and Its Integration within PBPK Models to Predict Inhalation Pharmacokinetics in Humans.QSARs for PBPK modelling of environmental contaminants.Molecular modelling of CYP2B6 based on homology with the CYP2C5 crystal structure: analysis of enzyme-substrate interactions.Quantitative structure-activity relationships (QSARs) for inhibitors and substrates of CYP2B enzymes: importance of compound lipophilicity in explanation of potency differences.Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris.
P2860

Baseline lipophilicity relationships in human cytochromes P450 associated with drug metabolism.

Item
http://www.wikidata.org/entity/Q35085025
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Baseline lipophilicity relatio ...... sociated with drug metabolism.
@ast
Baseline lipophilicity relatio ...... sociated with drug metabolism.
@en
type
label
Baseline lipophilicity relatio ...... sociated with drug metabolism.
@ast
Baseline lipophilicity relatio ...... sociated with drug metabolism.
@en
prefLabel
Baseline lipophilicity relatio ...... sociated with drug metabolism.
@ast
Baseline lipophilicity relatio ...... sociated with drug metabolism.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Baseline lipophilicity relatio ...... sociated with drug metabolism.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698