Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity.

Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity.

Item
http://www.wikidata.org/entity/Q37514128
Structural features of cytochromes P450 and ligands that affect drug metabolism as revealed by X-ray crystallography and NMR.Predictive models for cytochrome p450 isozymes based on quantitative high throughput screening dataPredictive approaches to increase absorption of compounds during lead optimisation.Human CYPs involved in drug metabolism: structures, substrates and binding affinities.Conformational plasticity and structure/function relationships in cytochromes P450.Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling.Quantitative Property-Property Relationship for Screening-Level Prediction of Intrinsic Clearance of Volatile Organic Chemicals in Rats and Its Integration within PBPK Models to Predict Inhalation Pharmacokinetics in Humans.ADME
P2860

Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity.

Item
http://www.wikidata.org/entity/Q37514128
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Human P450s involved in drug m ...... ectivity and binding affinity.
@en
Human P450s involved in drug m ...... ectivity and binding affinity.
@nl
type
label
Human P450s involved in drug m ...... ectivity and binding affinity.
@en
Human P450s involved in drug m ...... ectivity and binding affinity.
@nl
prefLabel
Human P450s involved in drug m ...... ectivity and binding affinity.
@en
Human P450s involved in drug m ...... ectivity and binding affinity.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Human P450s involved in drug m ...... ectivity and binding affinity.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698