Structure based design, synthesis, pharmacophore modeling, virtual screening, and molecular docking studies for identification of novel cyclophilin D inhibitors.

Structure based design, synthesis, pharmacophore modeling, virtual screening, and molecular docking studies for identification of novel cyclophilin D inhibitors.

Item
http://www.wikidata.org/entity/Q35098725
Molecular docking and structure-based drug design strategiesHigh-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 moleculesDetermination of small molecule ABAD inhibitors crossing blood-brain barrier and pharmacokineticsDiscovery of new [Formula: see text] proteasome inhibitors using a knowledge-based computational screening approach.Identification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial DysfunctionDesign, Synthesis, and in vitro and in vivo Evaluations of (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides/sulfonates as Highly Potent Tubulin Polymerization Inhibitors.Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds.A Mitocentric View of Alzheimer's Disease.Target-based molecular modeling strategies for schistosomiasis drug discovery.Prospects for therapeutic mitochondrial transplantation.Antimicrobial action of methanolic seed extracts of Syzygium cumini Linn. on Bacillus subtilis.A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K.Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer's Disease.Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction.Mitochondrial Perturbation in Alzheimer's Disease and Diabetes.Alzheimer: A decade of drug design. Why molecular topology can be an extra edge.
P2860

Structure based design, synthesis, pharmacophore modeling, virtual screening, and molecular docking studies for identification of novel cyclophilin D inhibitors.

Item
http://www.wikidata.org/entity/Q35098725
description
2014 nî lūn-bûn
@nan
2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structure based design, synthe ...... ovel cyclophilin D inhibitors.
@ast
Structure based design, synthe ...... ovel cyclophilin D inhibitors.
@en
type
label
Structure based design, synthe ...... ovel cyclophilin D inhibitors.
@ast
Structure based design, synthe ...... ovel cyclophilin D inhibitors.
@en
prefLabel
Structure based design, synthe ...... ovel cyclophilin D inhibitors.
@ast
Structure based design, synthe ...... ovel cyclophilin D inhibitors.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Structure based design, synthe ...... ovel cyclophilin D inhibitors.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P921
P932