Identification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial Dysfunction

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http://www.wikidata.org/entity/Q36681747

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

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2016年论文

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2016年论文

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name

Identification of a Small Mole ...... ated Mitochondrial Dysfunction

@ast

Identification of a Small Mole ...... ated Mitochondrial Dysfunction

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type

Item

label

Identification of a Small Mole ...... ated Mitochondrial Dysfunction

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Identification of a Small Mole ...... ated Mitochondrial Dysfunction

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prefLabel

Identification of a Small Mole ...... ated Mitochondrial Dysfunction

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Identification of a Small Mole ...... ated Mitochondrial Dysfunction

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P1476

Identification of a Small Mole ...... ated Mitochondrial Dysfunction

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P2093

Anuradha Roy

http://www.w3.org/2001/XMLSchema#string

Du Fang

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Jianping Li

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Koteswara Rao Valasani

http://www.w3.org/2001/XMLSchema#string

Qing Yu

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Qinru Sun

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Shirley ShiDu Yan

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Yaopeng Guo

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Zhihua Zhang

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P2860

Antamanide, a derivative of Amanita phalloides, is a novel inhibitor of the mitochondrial permeability transition pore

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction

Mitochondrial permeability transition pore is a potential drug target for neurodegeneration

Structure-Based Design of Highly Selective β-Secretase Inhibitors: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal Structure

A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases

Progress in the development of beta-secretase inhibitors for Alzheimer's disease.

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons

Structure based design, synthesis, pharmacophore modeling, virtual screening, and molecular docking studies for identification of novel cyclophilin D inhibitors.

Oxidative stress-mediated activation of extracellular signal-regulated kinase contributes to mild cognitive impairment-related mitochondrial dysfunction

P304

294-299

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scholarly article

P356

10.1021/ACSMEDCHEMLETT.5B00451

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P433

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P478

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2016-01-06T00:00:00Z

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26985318

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4789676

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