Cerebral expression of interleukin-12 induces neurological disease via differential pathways and recruits antigen-specific T cells in virus-infected mice.
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TNF-overexpression in Borna disease virus-infected mouse brains triggers inflammatory reaction and epileptic seizuresTrafficking of immune cells in the central nervous systemTransgenic models for cytokine-induced neurological disease.Innate immune responses in NF-kappaB-repressing factor-deficient miceGlucocorticoid treatment of MCMV infected newborn mice attenuates CNS inflammation and limits deficits in cerebellar development.Antiviral CD8 T cells recognize borna disease virus antigen transgenically expressed in either neurons or astrocytesInterferon-gamma prevents death of bystander neurons during CD8 T cell responses in the brain.Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12.CD8 T cells require gamma interferon to clear borna disease virus from the brain and prevent immune system-mediated neuronal damage.Downregulation of an astrocyte-derived inflammatory protein, S100B, reduces vascular inflammatory responses in brains persistently infected with Borna disease virus.Viral-induced inflammation is accompanied by beta-amyloid plaque reduction in brains of amyloid precursor protein transgenic Tg2576 mice.
P2860
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P2860
Cerebral expression of interleukin-12 induces neurological disease via differential pathways and recruits antigen-specific T cells in virus-infected mice.
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Cerebral expression of interle ...... cells in virus-infected mice.
@ast
Cerebral expression of interle ...... cells in virus-infected mice.
@en
type
label
Cerebral expression of interle ...... cells in virus-infected mice.
@ast
Cerebral expression of interle ...... cells in virus-infected mice.
@en
prefLabel
Cerebral expression of interle ...... cells in virus-infected mice.
@ast
Cerebral expression of interle ...... cells in virus-infected mice.
@en
P2093
P2860
P1476
Cerebral expression of interle ...... cells in virus-infected mice.
@en
P2093
Axel Pagenstecher
Jürgen Hausmann
Markus Hofer
Peter Staeheli
P2860
P304
P356
10.1016/S0002-9440(10)63356-1
P407
P577
2004-09-01T00:00:00Z