Deletions affecting hemolytic and toxin activities of Bordetella pertussis adenylate cyclase.
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Bordetella adenylate cyclase toxin mobilizes its beta2 integrin receptor into lipid rafts to accomplish translocation across target cell membrane in two stepsMolecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies.RTX proteins: a highly diverse family secreted by a common mechanismMolecular analysis of a metalloprotease from Proteus mirabilisCalcium influx rescues adenylate cyclase-hemolysin from rapid cell membrane removal and enables phagocyte permeabilization by toxin pores.Albumin, in the Presence of Calcium, Elicits a Massive Increase in Extracellular Bordetella Adenylate Cyclase Toxin.Characterization of binding of adenylate cyclase toxin to target cells by flow cytometry.Translocation-specific conformation of adenylate cyclase toxin from Bordetella pertussis inhibits toxin-mediated hemolysis.Cell cycle arrest induced by the bacterial adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis.Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size.CyaC-mediated activation is important not only for toxic but also for protective activities of Bordetella pertussis adenylate cyclase-hemolysin.Virulence of Bordetella bronchiseptica: role of adenylate cyclase-hemolysin.Identification of the YopE and YopH domains required for secretion and internalization into the cytosol of macrophages, using the cyaA gene fusion approach.Suppression of platelet aggregation by Bordetella pertussis adenylate cyclase toxin.Stimulation of Bordetella pertussis adenylate cyclase toxin intoxication by its hemolysin domainEvidence for phenotypic bistability resulting from transcriptional interference of bvgAS in Bordetella bronchiseptica.Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic formThe C-terminal domain is essential for protective activity of the Bordetella pertussis adenylate cyclase-hemolysin.Cell-invasive activity of epitope-tagged adenylate cyclase of Bordetella pertussis allows in vitro presentation of a foreign epitope to CD8+ cytotoxic T cells.Charge-dependent translocation of Bordetella pertussis adenylate cyclase toxin into eukaryotic cells: implication for the in vivo delivery of CD8(+) T cell epitopes into antigen-presenting cells.RTX cytotoxins recognize beta2 integrin receptors through N-linked oligosaccharidesCloning and characterization of btr, a Bordetella pertussis gene encoding an FNR-like transcriptional regulator.Targeted mutations that ablate either the adenylate cyclase or hemolysin function of the bifunctional cyaA toxin of Bordetella pertussis abolish virulenceBordetella pertussis adenylate cyclase toxin translocation across a tethered lipid bilayerDelivery of CD8(+) T-cell epitopes into major histocompatibility complex class I antigen presentation pathway by Bordetella pertussis adenylate cyclase: delineation of cell invasive structures and permissive insertion sites.Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain.Identification of a region that assists membrane insertion and translocation of the catalytic domain of Bordetella pertussis CyaA toxin.Acylation of Escherichia coli hemolysin: a unique protein lipidation mechanism underlying toxin function.Bordetella adenylate cyclase toxin promotes calcium entry into both CD11b+ and CD11b- cells through cAMP-dependent L-type-like calcium channels.Structure-function studies of the adenylate cyclase toxin of Bordetella pertussis and the leukotoxin of Pasteurella haemolytica by heterologous C protein activation and construction of hybrid proteinsCyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis.Pore-forming and enzymatic activities of Bordetella pertussis adenylate cyclase toxin synergize in promoting lysis of monocytes.Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin.The conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin.Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes.Bordetella Pertussis Adenylate Cyclase Toxin Does Not Possess a Phospholipase A Activity; Serine 606 and Aspartate 1079 Residues Are Not Involved in Target Cell Delivery of the Adenylyl Cyclase Enzyme Domain.
P2860
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P2860
Deletions affecting hemolytic and toxin activities of Bordetella pertussis adenylate cyclase.
description
1990 nî lūn-bûn
@nan
1990 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Deletions affecting hemolytic ...... a pertussis adenylate cyclase.
@ast
Deletions affecting hemolytic ...... a pertussis adenylate cyclase.
@en
type
label
Deletions affecting hemolytic ...... a pertussis adenylate cyclase.
@ast
Deletions affecting hemolytic ...... a pertussis adenylate cyclase.
@en
prefLabel
Deletions affecting hemolytic ...... a pertussis adenylate cyclase.
@ast
Deletions affecting hemolytic ...... a pertussis adenylate cyclase.
@en
P2093
P2860
P1476
Deletions affecting hemolytic ...... a pertussis adenylate cyclase.
@en
P2093
P2860
P304
P407
P577
1990-10-01T00:00:00Z