Regulation of pulmonary and systemic bacterial lipopolysaccharide responses in transgenic mice expressing human elafin
about
Elafin is a biomarker of graft-versus-host disease of the skinAntimicrobial activity of murine lung cells against Staphylococcus aureus is increased in vitro and in vivo after elafin gene transfer.Functional characterization of polymorphisms in the peptidase inhibitor 3 (elafin) gene and validation of their contribution to risk of acute respiratory distress syndrome.Gene set signature of reversal reaction type I in leprosy patients.Neonatal mice genetically modified to express the elastase inhibitor elafin are protected against the adverse effects of mechanical ventilation on lung growthEndogenous pulmonary antibiotics.Antiviral activity of trappin-2 and elafin in vitro and in vivo against genital herpes.Trappin-2 promotes early clearance of Pseudomonas aeruginosa through CD14-dependent macrophage activation and neutrophil recruitmentThe antimicrobial molecule trappin-2/elafin has anti-parasitic properties and is protective in vivo in a murine model of cerebral malaria.Secretory leukocyte protease inhibitor and elafin/trappin-2: versatile mucosal antimicrobials and regulators of immunity.Expression of secretory leukocyte protease inhibitor and elafin in human fallopian tube and in an in-vitro model of Chlamydia trachomatis infection.WAP domain proteins as modulators of mucosal immunity.SLPI and elafin: multifunctional antiproteases of the WFDC family.SLPI and trappin-2 as therapeutic agents to target airway serine proteases in inflammatory lung diseases: current and future directions.Pseudomonas aeruginosa LasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator-IL-6-antimicrobial-repair pathway.Protease inhibitors derived from elafin and SLPI and engineered to have enhanced specificity towards neutrophil serine proteases.Differential effects of periopathogens on host protease inhibitors SLPI, elafin, SCCA1, and SCCA2.The antimicrobial/elastase inhibitor elafin regulates lung dendritic cells and adaptive immunity.The antimicrobial antiproteinase elafin binds to lipopolysaccharide and modulates macrophage responses.Effects of tumor necrosis factor-alpha (TNF alpha) in epidermal keratinocytes revealed using global transcriptional profiling.
P2860
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P2860
Regulation of pulmonary and systemic bacterial lipopolysaccharide responses in transgenic mice expressing human elafin
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Regulation of pulmonary and sy ...... c mice expressing human elafin
@ast
Regulation of pulmonary and sy ...... c mice expressing human elafin
@en
type
label
Regulation of pulmonary and sy ...... c mice expressing human elafin
@ast
Regulation of pulmonary and sy ...... c mice expressing human elafin
@en
prefLabel
Regulation of pulmonary and sy ...... c mice expressing human elafin
@ast
Regulation of pulmonary and sy ...... c mice expressing human elafin
@en
P2093
P2860
P1476
Regulation of pulmonary and sy ...... c mice expressing human elafin
@en
P2093
G A Cunningham
P2860
P304
P356
10.1128/IAI.71.7.3766-3774.2003
P407
P577
2003-07-01T00:00:00Z