Abundant non-canonical dUTP found in primary human macrophages drives its frequent incorporation by HIV-1 reverse transcriptase.

Abundant non-canonical dUTP found in primary human macrophages drives its frequent incorporation by HIV-1 reverse transcriptase.

Item
http://www.wikidata.org/entity/Q35107515
Molecular mechanisms of HIV immune evasion of the innate immune response in myeloid cellsGTP activator and dNTP substrates of HIV-1 restriction factor SAMHD1 generate a long-lived activated stateTight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages.Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration.Innate immune sensing of HIV-1 by dendritic cells.Effect of ribonucleotides embedded in a DNA template on HIV-1 reverse transcription kinetics and fidelityHIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteinsIntracellular nucleotide levels and the control of retroviral infections.Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells.Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration.Pre-steady state kinetic analysis of HIV-1 reverse transcriptase for non-canonical ribonucleoside triphosphate incorporation and DNA synthesis from ribonucleoside-containing DNA template.The Impact of Macrophage Nucleotide Pools on HIV-1 Reverse Transcription, Viral Replication, and the Development of Novel Antiviral Agents.Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G.HIV-1 Vpr Reprograms CLR4 E3 Ubiquitin Ligase to Antagonize Exonuclease 1-Mediated Restriction of HIV-1 Infection
P2860

Abundant non-canonical dUTP found in primary human macrophages drives its frequent incorporation by HIV-1 reverse transcriptase.

Item
http://www.wikidata.org/entity/Q35107515
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
@wuu
name
Abundant non-canonical dUTP fo ...... y HIV-1 reverse transcriptase.
@ast
Abundant non-canonical dUTP fo ...... y HIV-1 reverse transcriptase.
@en
type
label
Abundant non-canonical dUTP fo ...... y HIV-1 reverse transcriptase.
@ast
Abundant non-canonical dUTP fo ...... y HIV-1 reverse transcriptase.
@en
prefLabel
Abundant non-canonical dUTP fo ...... y HIV-1 reverse transcriptase.
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Abundant non-canonical dUTP fo ...... y HIV-1 reverse transcriptase.
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Abundant non-canonical dUTP fo ...... y HIV-1 reverse transcriptase.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932