Chromosomal translocations involving the MLL gene: molecular mechanisms.
about
CBX8, a polycomb group protein, is essential for MLL-AF9-induced leukemogenesisThe PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesisThe transposase domain protein Metnase/SETMAR suppresses chromosomal translocationsCommon features of chromatin in aging and cancer: cause or coincidence?Cancer epigenetics drug discovery and development: the challenge of hitting the markReplication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposideDisordered epigenetic regulation in MLL-related leukemia.The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.Signatures of selection in fusion transcripts resulting from chromosomal translocations in human cancerMLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signaturesGenetic rearrangement MLL/AF4 is most frequent in children with acute lymphoblastic leukemias in Mexico City.Efficient repair of DNA double-strand breaks in malignant cells with structural instability.Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon.Novel domain combinations in proteins encoded by chimeric transcriptsECSASB2 mediates MLL degradation during hematopoietic differentiationStress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cellsA subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.Mechanisms leading to nonrandom, nonhomologous chromosomal translocations in leukemiaThe cellular etiology of chromosome translocations.Mechanisms of leukemia translocationsThe heterogeneity of pediatric MLL-rearranged acute myeloid leukemia.Genome Organization Drives Chromosome Fragility.Identification of acquired copy number alterations and uniparental disomies in cytogenetically normal acute myeloid leukemia using high-resolution single-nucleotide polymorphism analysis.The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia.PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia.Acute Myeloid LeukemiaTAP: a targeted clinical genomics pipeline for detecting transcript variants using RNA-seq data
P2860
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P2860
Chromosomal translocations involving the MLL gene: molecular mechanisms.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Chromosomal translocations involving the MLL gene: molecular mechanisms.
@ast
Chromosomal translocations involving the MLL gene: molecular mechanisms.
@en
type
label
Chromosomal translocations involving the MLL gene: molecular mechanisms.
@ast
Chromosomal translocations involving the MLL gene: molecular mechanisms.
@en
prefLabel
Chromosomal translocations involving the MLL gene: molecular mechanisms.
@ast
Chromosomal translocations involving the MLL gene: molecular mechanisms.
@en
P2860
P1433
P1476
Chromosomal translocations involving the MLL gene: molecular mechanisms.
@en
P2093
Peter D Aplan
P2860
P304
P356
10.1016/J.DNAREP.2006.05.034
P577
2006-06-21T00:00:00Z