Transcription factor BORIS (Brother of the Regulator of Imprinted Sites) directly induces expression of a cancer-testis antigen, TSP50, through regulated binding of BORIS to the promoter - Wikidata - awgldk - TriplyDB

Transcription factor BORIS (Brother of the Regulator of Imprinted Sites) directly induces expression of a cancer-testis antigen, TSP50, through regulated binding of BORIS to the promoter

Transcription factor BORIS (Brother of the Regulator of Imprinted Sites) directly induces expression of a cancer-testis antigen, TSP50, through regulated binding of BORIS to the promoter

http://www.wikidata.org/entity/Q35144879

about

Dose-dependent activation of putative oncogene SBSN by BORIS The cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elements Expression of the CTCFL Gene during Mouse Embryogenesis Causes Growth Retardation, Postnatal Lethality, and Dysregulation of the Transforming Growth Factor β Pathway.Identification of CTCF as a master regulator of the clustered protocadherin genes.Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions.Testis-specific transcriptional regulators selectively occupy BORIS-bound CTCF target regions in mouse male germ cells.Cancer testes antigens in breast cancer: biological role, regulation, and therapeutic applicability.Expression analysis of BORIS during pluripotent, differentiated, cancerous, and non-cancerous cell states.25-methoxyl-dammarane-3β, 12β, 20-triol and artemisinin synergistically inhibit MDA-MB-231 cell proliferation through downregulation of testes-specific protease 50 (TSP50) expression.Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers.Expression of the cancer-testis antigen BORIS correlates with prostate cancer.The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells.The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner.The downregulation of putative anticancer target BORIS/CTCFL in an addicted myeloid cancer cell line modulates the expression of multiple protein coding and ncRNA genes.Discovering a binary CTCF code with a little help from BORIS.Testes-specific protease 50 as an independent risk factor for poor prognosis in patients with non-small cell lung cancer.BORIS: a key regulator of cancer stemness

P2860

Q28727517-6D01FA5E-4D75-4AD9-BFB9-44F0BBE355DD Q28828237-76CF4B65-4295-4A70-98E5-1617CDE86175 Q35690067-E3BFB8DF-BB9C-4ECE-BC56-03176D045A92 Q35906094-BFB882E7-B766-42C1-9CE9-233976CD58F5 Q36034801-80708937-EE22-417E-86C8-5D5BE3B3EE02 Q37618285-45022420-4CC1-4D38-BA58-79B6D080A506 Q38053488-B564DF4A-6532-44BB-BF74-D3F68B68E4DB Q38306384-91196529-3D3F-4335-BA5F-630CADE76D08 Q38737154-FBADD556-7BA7-4D63-8AED-3A517B35764A Q38948541-72C204B4-2AC2-43A3-9ACC-42886758F315 Q39079438-83037FA5-CDE8-47BB-9475-B8B079408C9B Q39172013-8C83A245-C933-4440-9FEA-0A3436906235 Q42121580-13CF3135-5C65-43BB-8D43-2C277FA1B366 Q42778353-0F9A42CD-9CAB-4528-BDCC-C3B03AEE6BA0 Q48114058-B7B0A85F-1FC8-41D0-BF05-AF39D4F2B3A2 Q55128312-4D132E3F-4764-487C-A9E7-968A4CF94718 Q57482782-6717C11F-AF0B-4CD7-A6E7-67809FC01027

P2860

Transcription factor BORIS (Brother of the Regulator of Imprinted Sites) directly induces expression of a cancer-testis antigen, TSP50, through regulated binding of BORIS to the promoter

http://www.wikidata.org/entity/Q35144879

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Transcription factor BORIS (Br ...... nding of BORIS to the promoter

@ast

Transcription factor BORIS (Br ...... nding of BORIS to the promoter

@en

type

label

Transcription factor BORIS (Br ...... nding of BORIS to the promoter

@ast

Transcription factor BORIS (Br ...... nding of BORIS to the promoter

@en

prefLabel

Transcription factor BORIS (Br ...... nding of BORIS to the promoter

@ast

Transcription factor BORIS (Br ...... nding of BORIS to the promoter

@en

P1433

Q35144879-9FE9C24E-48D9-4D91-A8A5-E41ED89304B7

P1476

Q35144879-F162AED0-CE06-49D4-BF08-9F48217C091F

P2093

Q35144879-339E02EE-6A6E-44BC-939F-A2FC6E6C9E4D

Q35144879-961B6DC9-FC23-4686-98E5-4AA52BF3A0CB

Q35144879-9E4157FC-D9F8-4E40-AE9E-446A9BE6A55D

Q35144879-AAD93174-AA6E-4122-A377-448CDB8B1BEF

Q35144879-B3B2F34B-C042-40C6-9915-788F4AF74B75

P2860

Q35144879-0222C822-B5F0-4582-819A-010D572D2AFE

Q35144879-0B677EF9-8CAD-42CB-9379-2990574573CA

Q35144879-0FFB6EB4-A277-4C24-97A9-350176E7C101

Q35144879-1479B21E-DABA-45AF-8302-4A0B4A3EE051

Q35144879-28595CB9-7B70-45F0-AF2F-A052CE5AEA90

Q35144879-34C52B70-E966-4871-A40B-833B27AC9A5F

Q35144879-361A616F-BBBA-4A6A-910A-14A9F731B389

Q35144879-36D583B1-34FE-4BAC-AB1E-B62053768E9F

Q35144879-3B853F3E-C801-43B7-9D0E-DD5FBCE2D3F1

Q35144879-411EEDEB-AD07-4881-BE75-571EE996E850

P304

Q35144879-18023DF9-4408-40B9-8A80-DCF1D4B29D0D

P31

Q35144879-DA1786D0-3BC3-4D00-AFB6-99458F7C870C

P356

Q35144879-C61DF0DD-556C-49AC-B5CC-7C578B75F977

P407

Q35144879-E4D2EC73-E8C5-4861-889C-A8BFBCF82E2A

P433

Q35144879-55675BF1-DDCF-4DD9-AB17-DEC1D3B51925

P478

Q35144879-BC86D70A-4313-4745-BEB6-35F557751AE2

P50

Q35144879-0D74F085-6899-47B1-912B-5771539CF341

Q35144879-F54E9E93-BDB0-4406-B485-1C4797D317F8

P577

Q35144879-BA13C9AE-4C38-4C2F-9F8B-C5BC71BABE95

P5875

Q35144879-3B3FCE0F-D8C8-4F89-9995-FC0BFA917012

P698

Q35144879-DAB46925-B3DF-4DB7-80ED-B8F9E1CBE9E2

P932

Q35144879-C8EF108A-F48C-4D5D-A5B0-4C095B9B6BAC

P356

JBC.M111.243576

P1433

Journal of Biological Chemistry

P1476

Transcription factor BORIS (Br ...... nding of BORIS to the promoter

@en

P2093

Alexander A Vostrov

http://www.w3.org/2001/XMLSchema#string

Dmitri Loukinov

http://www.w3.org/2001/XMLSchema#string

Elena M Pugacheva

http://www.w3.org/2001/XMLSchema#string

Natsuki Kosaka-Suzuki

http://www.w3.org/2001/XMLSchema#string

Teruhiko Suzuki

http://www.w3.org/2001/XMLSchema#string

P2860

The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome

CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2

TSP50 encodes a testis-specific protease and is negatively regulated by p53

The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation

An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions

Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells

BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.

A chromatin insulator-like element in the herpes simplex virus type 1 latency-associated transcript region binds CCCTC-binding factor and displays enhancer-blocking and silencing activities.

CTCF: master weaver of the genome

P304

27378-27388

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M111.243576

http://www.w3.org/2001/XMLSchema#string

P407

P433

31

http://www.w3.org/2001/XMLSchema#string

P478

286

http://www.w3.org/2001/XMLSchema#string

P50

Herbert C. Morse

Victor V Lobanenkov

P577

2011-06-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51207011

http://www.w3.org/2001/XMLSchema#string

P698

21659515

http://www.w3.org/2001/XMLSchema#string

P932

3149331

http://www.w3.org/2001/XMLSchema#string