TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice. - Wikidata - awgldk - TriplyDB

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

http://www.wikidata.org/entity/Q35145453

about

Cellular Biomechanics in Drug Screening and Evaluation: Mechanopharmacology TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye.Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain.The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart.Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas High-Magnitude and/or High-Frequency Mechanical Strain Promotes Peripapillary Scleral Myofibroblast Differentiation.TRPV4 associates environmental temperature and sex determination in the American alligator TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis.Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities.Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype The matricellular protein CCN1 enhances TGF-β1/SMAD3-dependent profibrotic signaling in fibroblasts and contributes to fibrogenic responses to lung injury.Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease Mechanosensing by the α6-integrin confers an invasive fibroblast phenotype and mediates lung fibrosis.miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways.Autocrine lysophosphatidic acid signaling activates β-catenin and promotes lung allograft fibrosis.Calcium Homeostasis and Ionic Mechanisms in Pulmonary Fibroblasts.TRPV4 channels: physiological and pathological role in cardiovascular system.Update in Interstitial Lung Disease 2014.TRP functions in the broncho-pulmonary system.Newer developments in idiopathic pulmonary fibrosis in the era of anti-fibrotic medications.The role of stretch-activated ion channels in acute respiratory distress syndrome: finally a new target?Molecular networks underlying myofibroblast fate and fibrosis.Morphogenetics in brown, beige and white fat development.Myofibroblasts and inflammatory cells as players of cardiac fibrosis.TRPV4 ion channel is a novel regulator of dermal myofibroblast differentiation.The Role of Transient Receptor Potential Vanilloid 4 in Pulmonary Inflammatory Diseases.MRTFs- master regulators of EMT.The emerging role of transient receptor potential channels in chronic lung disease.Congenital diaphragmatic hernias: from genes to mechanisms to therapies.Disruption of Calcium Signaling in Fibroblasts and Attenuation of Bleomycin-Induced Fibrosis by Nifedipine.Structural determinants of 5',6'-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel.Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics-derived composite score.Mechanosensing and fibrosis.Cytokine-Ion Channel Interactions in Pulmonary Inflammation.Redirecting TGF-β Signaling through the β-Catenin/Foxo Complex Prevents Kidney Fibrosis.Transient receptor potential vanilloid 4 (TRPV4) activation by arachidonic acid requires protein kinase A-mediated phosphorylation.Telomere Damage Response and Low-Grade Inflammation.Extracellular matrix in lung development, homeostasis and disease.AMP-activated protein kinase/myocardin-related transcription factor-A signaling regulates fibroblast activation and renal fibrosis.

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P2860

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

http://www.wikidata.org/entity/Q35145453

description

2014 nî lūn-bûn

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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

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TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

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TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

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TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

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prefLabel

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

@ast

TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice.

@en

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Journal of Clinical Investigation

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TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice

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P2093

Charles K Thodeti

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Daniel J Tschumperlin

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David X Zhang

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Kathryn A Niese

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Lisa M Grove

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Magdalene M Moran

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Mitchell A Olman

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Sailaja Paruchuri

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Shaik O Rahaman

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Sudakshina Ghosh

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P2860

An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure

Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C

Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes

Recent developments in myofibroblast biology: paradigms for connective tissue remodeling

Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function

Cellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis

Transient receptor potential channels as therapeutic targets

A placebo-controlled randomized trial of warfarin in idiopathic pulmonary fibrosis

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5225-5238

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10.1172/JCI75331

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12

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124

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Rachel G Scheraga

Brian D Southern

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2014-11-03T00:00:00Z

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267755328

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25365224

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pulmonary fibrosis

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4348970

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