A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses.
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MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics.FeverBinding specificity of Toll-like receptor cytoplasmic domainsToll-Like Receptors in the Pathogenesis of Autoimmune DiseasesToll-like receptors in systemic lupus erythematosus: potential targets for therapeutic interventionRole of innate immunity in the development of hepatocellular carcinomaThe crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimerInflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseasesStructural and functional evidence for the role of the TLR2 DD loop in TLR1/TLR2 heterodimerization and signalingToll-Like Receptors and Cancer: MYD88 Mutation and Inflammation.MyD88 signaling regulates both host defense and immunopathogenesis during pneumocystis infectionGlaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signalingA small molecule that mimics the BB-loop in the Toll interleukin-1 (IL-1) receptor domain of MyD88 attenuates staphylococcal enterotoxin B-induced pro-inflammatory cytokine production and toxicity in miceInnate immune recognition of nucleic acids.Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus.Mammalian Toll-like receptors: to immunity and beyond.From cellular receptors to transduction-transcription pathways for cytokines: at which level should the inhibition be targeted in inflammation?The critical role of toll-like receptors--From microbial recognition to autoimmunity: A comprehensive review.Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: acute renal failure is dependent on MyD88 but not renal cell apoptosis.Targeting protein-protein interactions by rational design: mimicry of protein surfacesSuppression of TLR signaling by targeting TIR domain-containing proteinsCell-penetrating TIR BB loop decoy peptides a novel class of TLR signaling inhibitors and a tool to study topology of TIR-TIR interactions.Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response.Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins.Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein EFluorofenidone attenuates pulmonary inflammation and fibrosis via inhibiting the activation of NALP3 inflammasome and IL-1β/IL-1R1/MyD88/NF-κB pathway.Targeting TLR/IL-1R signalling in human diseases.Targeting Toll-like receptors for treatment of SLEToll-like receptor signaling pathways--therapeutic opportunities.Treating atherosclerosis: the potential of Toll-like receptors as therapeutic targets.Role of Toll-like receptors in liver health and disease.Taming inflammation by targeting cytokine signaling: new perspectives in the induction of transplantation tolerance.Toll/interleukin-1 receptor (TIR) domain-mediated cellular signaling pathways.Rational design of peptide derivatives for inhibition of MyD88-mediated toll-like receptor signaling in human peripheral blood mononuclear cells and epithelial cells exposed to Francisella tularensis.The Role of Toll-Like Receptors in Autoimmune Diseases through Failure of the Self-Recognition Mechanism.Mutational analysis identifies residues crucial for homodimerization of myeloid differentiation factor 88 (MyD88) and for its function in immune cells.Cytokines and cytokine networks target neurons to modulate long-term potentiation.Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer.Identification of interaction sites for dimerization and adapter recruitment in Toll/interleukin-1 receptor (TIR) domain of Toll-like receptor 4.
P2860
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P2860
A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A low molecular weight mimic o ...... 1 receptor-mediated responses.
@ast
A low molecular weight mimic o ...... 1 receptor-mediated responses.
@en
type
label
A low molecular weight mimic o ...... 1 receptor-mediated responses.
@ast
A low molecular weight mimic o ...... 1 receptor-mediated responses.
@en
prefLabel
A low molecular weight mimic o ...... 1 receptor-mediated responses.
@ast
A low molecular weight mimic o ...... 1 receptor-mediated responses.
@en
P2093
P2860
P356
P1476
A low molecular weight mimic o ...... 1 receptor-mediated responses.
@en
P2093
Alexander Shivanyuk
Janell Pemberton
M Margarita Behrens
Svetlana Gaidarova
P2860
P304
P356
10.1073/PNAS.0932746100
P407
P577
2003-06-10T00:00:00Z