Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.
about
Prion pathogenesis in the absence of NLRP3/ASC inflammasomesNLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity.Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease.Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesisEngulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner.MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state.Toll-like receptor 4 promotes α-synuclein clearance and survival of nigral dopaminergic neurons.Altered lymphocyte proliferation and innate immune function in scrapie 139A- and ME7-infected miceProtection of hippocampal neurogenesis from toll-like receptor 4-dependent innate immune activation by ablation of prostaglandin E2 receptor subtype EP1 or EP2.Absence of CD14 delays progression of prion diseases accompanied by increased microglial activation.Analysis of protein levels of 24 cytokines in scrapie agent-infected brain and glial cell cultures from mice differing in prion protein expression levelsA clear and present danger: endogenous ligands of Toll-like receptors.Toll-like receptors expression and signaling in glia cells in neuro-amyloidogenic diseases: towards future therapeutic applicationInnate immunity and neuroinflammation.Protective role of interferon regulatory factor 3-mediated signaling against prion infection.Conditional modulation of membrane protein expression in cultured cells mediated by prion protein recognition of short phosphorothioate oligodeoxynucleotides.Microglia in prion diseases.Toll-like receptor-mediated immune response inhibits prion propagation.Recombinant mouse prion protein alone or in combination with lipopolysaccharide alters expression of innate immunity genes in the colon of mice.Protective role of MyD88-independent innate immune responses against prion infection.Let's make microglia great again in neurodegenerative disorders.The human saliva metabolomeExpression of selected genes isolated from whole blood, liver and obex in lambs with experimental classical scrapie and healthy controls, showing a systemic innate immune response at the clinical end-stage
P2860
Q27316552-8A76956F-169B-4A05-822D-9DE8568F2AEBQ30446504-D80BF49D-8469-4AC2-A913-1828E55FEC60Q33997514-FF003429-C51D-485B-A010-B70CDB4E9850Q33999325-1F423FB8-60D4-4F69-BCA1-7D3FFB46853BQ34161546-C4275FFC-146E-4269-8D80-53737627F0DDQ34170278-7EACBF4F-D1C3-48A1-A474-0B86258C9CCBQ35167964-2652E81C-5218-4F03-AFB7-A85E5E3D3AD9Q36913127-3136B7A9-5493-430E-A5FA-E73A2F1193E1Q37197399-55F54975-281E-4DD4-93B3-2825121B503CQ37336725-233B381A-FCB9-46CA-992D-AF02F09852AEQ37410864-F95E6BE5-D0EA-483C-8D10-889A7E78CFC7Q37615169-2AD13D47-0E5E-402A-83BD-1DFD84F28A1FQ37779740-E70E1C6A-C055-4325-AB50-2FF8FAA7EC12Q38120744-D64D9D50-7D63-4BE0-8A44-65503615435FQ39387817-F88B70CE-39D0-491A-BDB0-55A3C4ED8B7DQ39620231-347909E7-F9BF-4B03-B617-72394217DA79Q40132256-6CBB881A-3A4F-414A-B41D-D027CC8E2DDBQ40790120-4241DA76-AF59-4C75-95F0-76BD30381283Q42005484-B3CDC396-CC6B-42E3-A87C-4BAC95E68932Q42018061-A75AAD49-9439-4798-B5B7-4F2CFB250032Q46926746-9EE95227-84DB-4FD8-B7A2-5FFAD1006C11Q57014230-3C8E9B15-11F8-4D87-8095-10E96530213FQ58748345-EB7D09D3-C2CF-44E2-AAD7-CE51B2E00570
P2860
Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.
@en
type
label
Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.
@en
prefLabel
Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.
@en
P2093
P2860
P356
P1433
P1476
Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.
@en
P2093
Bo Sook Kim
Daniel J Kerr
Daryl S Spinner
Eunkyue Park
Georgia B Schuller-Levis
Giuseppe Lafauci
Harry C Meeker
In Soo Cho
Jae Il Kim
Michael J Flory
P2860
P304
10701-10708
P356
10.1128/JVI.00522-08
P407
P577
2008-08-20T00:00:00Z