Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice. - Wikidata - awgldk - TriplyDB

Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.

Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.

http://www.wikidata.org/entity/Q36949606

about

Prion pathogenesis in the absence of NLRP3/ASC inflammasomes NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity.Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease.Transcriptomic analysis brings new insight into the biological role of the prion protein during mouse embryogenesis Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner.MicroRNA 146a (miR-146a) is over-expressed during prion disease and modulates the innate immune response and the microglial activation state.Toll-like receptor 4 promotes α-synuclein clearance and survival of nigral dopaminergic neurons.Altered lymphocyte proliferation and innate immune function in scrapie 139A- and ME7-infected mice Protection of hippocampal neurogenesis from toll-like receptor 4-dependent innate immune activation by ablation of prostaglandin E2 receptor subtype EP1 or EP2.Absence of CD14 delays progression of prion diseases accompanied by increased microglial activation.Analysis of protein levels of 24 cytokines in scrapie agent-infected brain and glial cell cultures from mice differing in prion protein expression levels A clear and present danger: endogenous ligands of Toll-like receptors.Toll-like receptors expression and signaling in glia cells in neuro-amyloidogenic diseases: towards future therapeutic application Innate immunity and neuroinflammation.Protective role of interferon regulatory factor 3-mediated signaling against prion infection.Conditional modulation of membrane protein expression in cultured cells mediated by prion protein recognition of short phosphorothioate oligodeoxynucleotides.Microglia in prion diseases.Toll-like receptor-mediated immune response inhibits prion propagation.Recombinant mouse prion protein alone or in combination with lipopolysaccharide alters expression of innate immunity genes in the colon of mice.Protective role of MyD88-independent innate immune responses against prion infection.Let's make microglia great again in neurodegenerative disorders.The human saliva metabolome Expression of selected genes isolated from whole blood, liver and obex in lambs with experimental classical scrapie and healthy controls, showing a systemic innate immune response at the clinical end-stage

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P2860

Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.

http://www.wikidata.org/entity/Q36949606

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.

@en

type

label

Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.

@en

prefLabel

Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.

@en

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Journal of Virology

P1476

Accelerated prion disease pathogenesis in Toll-like receptor 4 signaling-mutant mice.

@en

P2093

Bo Sook Kim

http://www.w3.org/2001/XMLSchema#string

Daniel J Kerr

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Daryl S Spinner

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Eunkyue Park

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Georgia B Schuller-Levis

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Giuseppe Lafauci

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Harry C Meeker

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In Soo Cho

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Jae Il Kim

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Michael J Flory

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P2860

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

Toll-like receptors in innate immunity

Prion pathogenesis in the absence of Toll-like receptor signalling

Modes of action of Freund's adjuvants in experimental models of autoimmune diseases.

Adenovirus RIDalphabeta complex inhibits lipopolysaccharide signaling without altering TLR4 cell surface expression.

A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses.

Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils.

Mutations in TLR4 signaling that lead to increased susceptibility to infection in humans: an overview.

P304

10701-10708

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scholarly article

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10.1128/JVI.00522-08

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P407

P433

21

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82

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Richard I. Carp

Richard J. Kascsak

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2008-08-20T00:00:00Z

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P698

18715916

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P921

Prion protein family

Toll-like receptor

P932

2573175

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