Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1-MAGE-A1 from a nonimmunized phage-Fab library.
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In vivo selection of engineered homing endonucleases using double-strand break induced homologous recombinationConformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificityRational development of high-affinity T-cell receptor-like antibodiesA phage display selected fab fragment with MHC class I-restricted specificity for MAGE-A1 allows for retargeting of primary human T lymphocytes.Recombinant antibodies for cancer diagnosis and therapy.Molecular studies of anti-HLA-A2 using light-chain shuffling: a structural model for HLA antibody binding.An hepatitis B virus surface antigen specific single chain of variable fragment derived from a natural immune antigen binding fragment phage display library is specifically internalized by HepG2.2.15 cells.Antitumor activity of immunotoxins with T-cell receptor-like specificity against human melanoma xenografts.Selection of human antibody fragments directed against tumor T-cell epitopes for adoptive T-cell therapy.T cell receptor (TCR) gene therapy to treat melanoma: lessons from clinical and preclinical studies.Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC- restricted T cell receptor-like specificity.Retargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor.Affinity maturation of antiHER2 monoclonal antibody MIL5 using an epitope-specific synthetic phage library by computational design.Survey of the year 2000 commercial optical biosensor literature.Telomerase as a universal tumor-associated antigen for cancer immunotherapy.An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells.Tumor antigens and proteomics from the point of view of the major histocompatibility complex peptides.Affinity maturation of T-cell receptor-like antibodies for Wilms tumor 1 peptide greatly enhances therapeutic potential.Targeting melanoma with immunoliposomes coupled to anti-MAGE A1 TCR-like single-chain antibody.T-cell receptor-like antibodies: novel reagents for clinical cancer immunology and immunotherapy.Stable, soluble, high-affinity, engineered T cell receptors: novel antibody-like proteins for specific targeting of peptide antigens.Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.TCR-like biomolecules target peptide/MHC Class I complexes on the surface of infected and cancerous cells.T-cell-receptor-like antibodies - generation, function and applications.Epitopes of the class I major histocompatibility complex (MHC-I) recognized in the syngeneic or allogeneic context predominantly linked to antigenic peptide loading to its binding groove.Therapeutic Antibodies against Intracellular Tumor AntigensConstruction and molecular characterization of a T-cell receptor-like antibody and CAR-T cells specific for minor histocompatibility antigen HA-1H.MHC-peptide-specific antibodies reveal inefficient presentation of an HLA-A*0201-restricted, Melan-A-derived peptide after active intracellular processing.Strategies for Bispecific Single Chain Antibody in Cancer Immunotherapy.Targeting Intracellular Antigens with pMHC-Binding Antibodies: A Phage Display Approach.On the path to TCR-directed therapeutics.An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity.A major histocompatibility complex-peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes: crystal structure of human leukocyte antigen (HLA)-A1-MAGE-A1 in complex with FAB-HYB3.Production of Antigen-Binding Fragment against O,O-Diethyl Organophosphorus Pesticides and Molecular Dynamics Simulations of Antibody Recognition.
P2860
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P2860
Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1-MAGE-A1 from a nonimmunized phage-Fab library.
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Direct selection of a human an ...... onimmunized phage-Fab library.
@ast
Direct selection of a human an ...... onimmunized phage-Fab library.
@en
type
label
Direct selection of a human an ...... onimmunized phage-Fab library.
@ast
Direct selection of a human an ...... onimmunized phage-Fab library.
@en
prefLabel
Direct selection of a human an ...... onimmunized phage-Fab library.
@ast
Direct selection of a human an ...... onimmunized phage-Fab library.
@en
P2093
P2860
P356
P1476
Direct selection of a human an ...... nonimmunized phage-Fab library
@en
P2093
B Uchanska-Ziegler
H R Hoogenboom
P G Coulie
S E Hufton
P2860
P304
P356
10.1073/PNAS.97.14.7969
P407
P577
2000-07-01T00:00:00Z