Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
about
The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesisComparative genomics and molecular dynamics of DNA repeats in eukaryotesAge-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington diseaseA novel GTPase, CRAG, mediates promyelocytic leukemia protein-associated nuclear body formation and degradation of expanded polyglutamine proteinAsialoerythropoietin is not effective in the R6/2 line of Huntington's disease miceTransgenic animal models for study of the pathogenesis of Huntington's disease and therapyMouse models of polyglutamine diseases: review and data table. Part IGranzyme M mediates a novel form of perforin-dependent cell deathApoptosis: a review of programmed cell deathLoss of GABAergic cortical neurons underlies the neuropathology of Lafora diseaseCellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic miceOmi / HtrA2 is relevant to the selective vulnerability of striatal neurons in Huntington's diseaseEffects of aging and sensory loss on glial cells in mouse visual and auditory cortices.Impaired brain creatine kinase activity in Huntington's disease.Induction of neostriatal neurogenesis slows disease progression in a transgenic murine model of Huntington diseaseAlterations in cortical excitation and inhibition in genetic mouse models of Huntington's disease.A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brainAlterations in the mouse and human proteome caused by Huntington's disease.Wheel running from a juvenile age delays onset of specific motor deficits but does not alter protein aggregate density in a mouse model of Huntington's disease.Cell death mechanisms and modulation in traumatic brain injury.Huntington disease models and human neuropathology: similarities and differencesThe histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1Loss of beta-III spectrin leads to Purkinje cell dysfunction recapitulating the behavior and neuropathology of spinocerebellar ataxia type 5 in humans.Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's disease.The latent stem cell population is retained in the hippocampus of transgenic Huntington's disease mice but not wild-type mice.Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell deathHIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells.Longitudinal characterization of brain atrophy of a Huntington's disease mouse model by automated morphological analyses of magnetic resonance images.BimEL as a possible molecular link between proteasome dysfunction and cell death induced by mutant huntingtinIdentification of new modulators and protein alterations in non-apoptotic programmed cell death.Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigsParaptosis: mediation by MAP kinases and inhibition by AIP-1/Alix.Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease.Developmental alterations in motor coordination and medium spiny neuron markers in mice lacking pgc-1αFerrostatins inhibit oxidative lipid damage and cell death in diverse disease modelsAnimal models of Huntington's disease.Cell death mechanisms in neurodegeneration.Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior.Amyloid-fibril formation. Proposed mechanisms and relevance to conformational disease.The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders.
P2860
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P2860
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
@ast
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
@en
type
label
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
@ast
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
@en
prefLabel
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
@ast
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
@en
P2093
P2860
P356
P1476
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
@en
P2093
P2860
P304
P356
10.1073/PNAS.110078997
P407
P577
2000-07-01T00:00:00Z