Mechanisms of glycosaminoglycan activation of the serpins in hemostasis.
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Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activationCrystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor XMolecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complexCoagulopathy in liver disease: Lack of an assessment toolThe influence of hinge region residue Glu-381 on antithrombin allostery and metastabilityStructure of native protein C inhibitor provides insight into its multiple functionsMolecular basis of factor IXa recognition by heparin-activated antithrombin revealed by a 1.7-A structure of the ternary complexPhysiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2Increased N-glycosylation efficiency by generation of an aromatic sequon on N135 of antithrombinMolecular recognition mechanisms of thrombin.Inhibitory properties of the P1 Tyr variant of antithrombin.A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor XaStructure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin.Allosteric activation of antithrombin critically depends upon hinge region extension.A translational block to HSPG synthesis permits BMP signaling in the early Drosophila embryo.Inhibition of antithrombin by Plasmodium falciparum histidine-rich protein IIHedgehogs like it sweet, too.Variant of PAI-2 gene is associated with coronary artery disease and recurrent coronary event risk in Chinese Han population.Surfen, a small molecule antagonist of heparan sulfateSerpins in thrombosis, hemostasis and fibrinolysisThe international normalized ratio to prioritize patients for liver transplantation: problems and possible solutions.The mucopolysaccharidoses: a success of molecular medicine.Looking at the proteases from a simple perspective.Clinical utility of viscoelastic tests of coagulation in patients with liver disease.Estimating glycosaminoglycan-protein interaction affinity: water dominates the specific antithrombin-heparin interaction.Adjustment of therapeutic LMWH to achieve specific target anti-FXa activity does not affect outcomes in pregnant patients with venous thromboembolism.Neuro-Coagulopathy: Blood Coagulation Factors in Central Nervous System Diseases.Zymogen activation of neurotrypsin and neurotrypsin-dependent agrin cleavage on the cell surface are enhanced by glycosaminoglycans.Localization of an antithrombin exosite that promotes rapid inhibition of factors Xa and IXa dependent on heparin activation of the serpin.Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery.Crystal structure of thrombin bound to heparin.Proteome analysis of testis from infertile protein C inhibitor-deficient mice reveals novel changes in serpin processing and prostaglandin metabolism.Residues Tyr253 and Glu255 in strand 3 of beta-sheet C of antithrombin are key determinants of an exosite made accessible by heparin activation to promote rapid inhibition of factors Xa and IXa.Inhibitory activity of the Drosophila melanogaster serpin Necrotic is dependent on lysine residues in the D-helix.Identification of serpins specific for activated protein C using a lysate-based screening assay.Dexamethasone Preconditioning in Cardiac Procedures Reduces Decreased Antithrombin Activity and Is Associated to Beneficial Outcomes: Role of Endothelium
P2860
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P2860
Mechanisms of glycosaminoglycan activation of the serpins in hemostasis.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Mechanisms of glycosaminoglycan activation of the serpins in hemostasis.
@ast
Mechanisms of glycosaminoglycan activation of the serpins in hemostasis.
@en
type
label
Mechanisms of glycosaminoglycan activation of the serpins in hemostasis.
@ast
Mechanisms of glycosaminoglycan activation of the serpins in hemostasis.
@en
prefLabel
Mechanisms of glycosaminoglycan activation of the serpins in hemostasis.
@ast
Mechanisms of glycosaminoglycan activation of the serpins in hemostasis.
@en
P2860
P1476
Mechanisms of glycosaminoglycan activation of the serpins in hemostasis.
@en
P2093
J A Huntington
P2860
P304
P356
10.1046/J.1538-7836.2003.00305.X
P577
2003-07-01T00:00:00Z