Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling.
about
Mutant Lrp1 knock-in mice generated by recombinase-mediated cassette exchange reveal differential importance of the NPXY motifs in the intracellular domain of LRP1 for normal fetal developmentLow-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasisStructural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domainTissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expressionDependence on endocytic receptor binding via a minimal binding motif underlies the differential prognostic profiles of SerpinE1 and SerpinB2 in cancer.Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression.The factor V light chain mediates the binding and endocytosis of plasma-derived factor V by megakaryocytes.Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells.Immunohistochemical localization of low density lipoprotein receptor-related protein 1 and alpha(2)-Macroglobulin in retinal and choroidal tissue of proliferative retinopathies.Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.Thrombin inhibition by serpins disrupts exosite IIBeyond endocytosis: LRP function in cell migration, proliferation and vascular permeability.LRP-1: functions, signaling and implications in kidney and other diseases.Factor VIII Interacts with the Endocytic Receptor Low-density Lipoprotein Receptor-related Protein 1 via an Extended Surface Comprising "Hot-Spot" Lysine Residues.Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signalingLipoprotein receptors--an evolutionarily ancient multifunctional receptor family.LRP-1 silencing prevents malignant cell invasion despite increased pericellular proteolytic activitiesCathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.Mapping the binding region on the low density lipoprotein receptor for blood coagulation factor VIII.Novel actions of tissue-type plasminogen activator in chronic kidney disease.Low-density lipoprotein receptor-related protein 1: new functions for an old molecule.Tissue plasminogen activator and inflammation: from phenotype to signaling mechanisms.Regulation of the Extracellular SERPINA5 (Protein C Inhibitor) Penetration Through Cellular Membranes.Matrix metalloproteinase-9 regulates tumor cell invasion through cleavage of protease nexin-1Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1.The functional role of the second NPXY motif of the LRP1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors.A unique function for LRP-1: a component of a two-receptor system mediating specific endocytosis of plasma-derived factor V by megakaryocytes.Cellular uptake of mammalian heparanase precursor involves low density lipoprotein receptor-related proteins, mannose 6-phosphate receptors, and heparan sulfate proteoglycans.Role of LRP-1 in cancer cell migration in 3-dimensional collagen matrix.A slow-cycling subpopulation of melanoma cells with highly invasive properties.Malaria circumsporozoite protein inhibits the respiratory burst in Kupffer cells.LRP1/CD91 is up-regulated in monocytes from patients with haemophilia A: a single-centre analysis.Sequences from the low density lipoprotein receptor-related protein (LRP) cytoplasmic domain enhance amyloid beta protein production via the beta-secretase pathway without altering amyloid precursor protein/LRP nuclear signaling.Obesity-related derangements of coagulation and fibrinolysis: a study of obesity-discordant monozygotic twin pairs.Standardized flow cytometry assay for identification of human monocytic heterogeneity and LRP1 expression in monocyte subpopulations: decreased expression of this receptor in nonclassical monocytes.Inhibitory activity of the Drosophila melanogaster serpin Necrotic is dependent on lysine residues in the D-helix.Amyloid efflux transporter expression at the blood-brain barrier declines in normal aging.
P2860
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P2860
Diverse role of LDL receptor-related protein in the clearance of proteases and in signaling.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Diverse role of LDL receptor-r ...... of proteases and in signaling.
@ast
Diverse role of LDL receptor-r ...... of proteases and in signaling.
@en
type
label
Diverse role of LDL receptor-r ...... of proteases and in signaling.
@ast
Diverse role of LDL receptor-r ...... of proteases and in signaling.
@en
prefLabel
Diverse role of LDL receptor-r ...... of proteases and in signaling.
@ast
Diverse role of LDL receptor-r ...... of proteases and in signaling.
@en
P2860
P1476
Diverse role of LDL receptor-r ...... of proteases and in signaling.
@en
P2093
Ranganathan S
Strickland DK
P2860
P304
P356
10.1046/J.1538-7836.2003.00330.X
P577
2003-07-01T00:00:00Z