The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation.
about
Targeting DNA repair pathways for cancer treatment: what's new?Role of the DNA base excision repair protein, APE1 in cisplatin, oxaliplatin, or carboplatin induced sensory neuropathySmall molecule activation of apurinic/apyrimidinic endonuclease 1 reduces DNA damage induced by cisplatin in cultured sensory neuronsAPE1, the DNA base excision repair protein, regulates the removal of platinum adducts in sensory neuronal cultures by NERMale Rat Germ Cells Display Age-Dependent and Cell-Specific Susceptibility in Response to Oxidative Stress Challenges.Base excision repair in physiology and pathology of the central nervous systemDNA damage response in peripheral nervous system: coping with cancer therapy-induced DNA lesionsGenetics of amyotrophic lateral sclerosis: an update.Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation.Base excision repair in the mammalian brain: implication for age related neurodegenerationChallenges and opportunities identifying therapeutic targets for chemotherapy-induced peripheral neuropathy resulting from oxidative DNA damage.A review on protein-protein interaction network of APE1/Ref-1 and its associated biological functions.Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models.Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral NeuropathyEnforced DNA repair enzymes rescue neurons from apoptosis induced by target deprivation and axotomy in mouse models of neurodegeneration.Apurinic/apyrimidinic endonuclease 1 upregulation reduces oxidative DNA damage and protects hippocampal neurons from ischemic injury.DNA damage mediates changes in neuronal sensitivity induced by the inflammatory mediators, MCP-1 and LPS, and can be reversed by enhancing the DNA repair function of APE1.Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic.Role of Ionizing Radiation in Neurodegenerative Diseases.Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival
P2860
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P2860
The repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The repair function of the mul ...... tive after ionizing radiation.
@ast
The repair function of the mul ...... tive after ionizing radiation.
@en
type
label
The repair function of the mul ...... tive after ionizing radiation.
@ast
The repair function of the mul ...... tive after ionizing radiation.
@en
prefLabel
The repair function of the mul ...... tive after ionizing radiation.
@ast
The repair function of the mul ...... tive after ionizing radiation.
@en
P2093
P2860
P1433
P1476
The repair function of the mul ...... tive after ionizing radiation.
@en
P2093
Chunlu Guo
Eric L Thompson
Mark R Kelley
Michael R Vasko
P2860
P304
P356
10.1016/J.DNAREP.2011.06.004
P577
2011-07-08T00:00:00Z