Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
about
The biology of the Ets1 proto-oncogeneSp100 interacts with ETS-1 and stimulates its transcriptional activityPhosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressorMolecular mechanisms of ETS transcription factor-mediated tumorigenesisRegulation of the transcription factor Ets-1 by DNA-mediated homo-dimerizationStructural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNAStructural basis of Ets1 activation by Runx1Constitutive activation of the ETS-1-miR-222 circuitry in metastatic melanomaTranscriptional regulation of PP2A-A alpha is mediated by multiple factors including AP-2alpha, CREB, ETS-1, and SP-1MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation.Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation.Conditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function.Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCFSynergy of aromatic residues and phosphoserines within the intrinsically disordered DNA-binding inhibitory elements of the Ets-1 transcription factorTranscriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4.The transcription factor ETS-1 mediates proinflammatory responses and neointima formation in carotid artery endoluminal vascular injury.Inhibitory effects of transcription factor Ikaros on the expression of liver cancer stem cell marker CD133 in hepatocellular carcinoma.The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region.A yeast one-hybrid and microfluidics-based pipeline to map mammalian gene regulatory networks.An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors.Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1Ets-1 is a negative regulator of Th17 differentiation.Review of Ets1 structure, function, and roles in immunityCK2 phosphorylation inactivates DNA binding by the papillomavirus E1 and E2 proteins.Transcription factor avian erythroblastosis virus E26 oncogen homolog-1 is a novel mediator of renal injury in salt-sensitive hypertension.Correlated motions and interactions at the onset of the DNA-induced partial unfolding of Ets-1.Highly cooperative recruitment of Ets-1 and release of autoinhibition by Pax5.The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus.The transcription factor E26 transformation-specific sequence-1 mediates neointima formation in arteriovenous fistula.Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment.Genome-Wide Identification of Target Genes for the Key B Cell Transcription Factor Ets1Genomic and biochemical insights into the specificity of ETS transcription factors.Regulation of endothelial cell development by ETS transcription factorsCyclin A is a mediator of p120E4F-dependent cell cycle arrest in G1.A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation.Tcra enhancer activation by inducible transcription factors downstream of pre-TCR signaling.Calcium regulation of GM-CSF by calmodulin-dependent kinase II phosphorylation of Ets1Transcriptional silencing of the ETS1 oncogene contributes to human granulocytic differentiationTime-dependent activation of Phox2a by the cyclic AMP pathway modulates onset and duration of p27Kip1 transcription.A role for mitogen-activated protein kinase and Ets-1 in the induction of interleukin-10 transcription by human immunodeficiency virus-1 Tat.
P2860
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P2860
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
@ast
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
@en
type
label
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
@ast
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
@en
prefLabel
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
@ast
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
@en
P2860
P1433
P1476
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
@en
P2093
B J Graves
D O Cowley
P2860
P304
P577
2000-02-01T00:00:00Z