about
Fosmidomycin plus clindamycin for treatment of pediatric patients aged 1 to 14 years with Plasmodium falciparum malariaGenomics-enabled discovery of phosphonate natural products and their biosynthetic pathwaysChemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparumStructure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycinLeveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomalleiNew N-Acetyltransferase Fold in the Structure and Mechanism of the Phosphonate Biosynthetic Enzyme FrbFCytidine derivatives as IspF inhibitors of Burkolderia pseudomalleiExperimental Genetics of Plasmodium berghei NFU in the Apicoplast Iron-Sulfur Cluster Biogenesis PathwayReconstitution of an apicoplast-localised electron transfer pathway involved in the isoprenoid biosynthesis of Plasmodium falciparumA chemical rescue screen identifies a Plasmodium falciparum apicoplast inhibitor targeting MEP isoprenoid precursor biosynthesisEcological networking of cystic fibrosis lung infections.Fragment screening of infectious disease targets in a structural genomics environmentShort-course regimens of artesunate-fosmidomycin in treatment of uncomplicated Plasmodium falciparum malaria.Gibberellin biosynthetic inhibitors make human malaria parasite Plasmodium falciparum cells swell and rupture to death.Semi-automated curation of metabolic models via flux balance analysis: a case study with Mycoplasma gallisepticumAntiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box.Drug discovery for human African trypanosomiasis: identification of novel scaffolds by the newly developed HTS SYBR Green assay for Trypanosoma brucei.Randomized controlled trial of fosmidomycin-clindamycin versus sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum malariaSuperessential reactions in metabolic networksInadequate efficacy of a new formulation of fosmidomycin-clindamycin combination in Mozambican children less than three years old with uncomplicated Plasmodium falciparum malaria.Resistance of Francisella novicida to fosmidomycin associated with mutations in the glycerol-3-phosphate transporter.Mycoplasma penetrans is capable of activating V gamma 9/V delta 2 T cells while other human pathogenic mycoplasmas fail to do soPlasmodium IspD (2-C-Methyl-D-erythritol 4-Phosphate Cytidyltransferase), an Essential and Druggable Antimalarial Target.Assessment of safety of the major antimalarial drugs.Emerging trends in metalloprotein inhibition.Biosynthesis of phosphonic and phosphinic acid natural products.The global portfolio of new antimalarial medicines under development.Trypanocidal drugs: mechanisms, resistance and new targets.Biochemistry of the non-mevalonate isoprenoid pathway.The isoprenoid-precursor dependence of Plasmodium spp.New approaches in antimalarial drug discovery and development: a review.Drug discovery and human African trypanosomiasis: a disease less neglected?Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection.Isoprenoid biosynthesis as a target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reducto-isomerase.Improved efficacy of fosmidomycin against Plasmodium and Mycobacterium species by combination with the cell-penetrating peptide octaarginine.Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum.Antiprotozoal activity of ferroquine.Microfluidics-based single cell analysis reveals drug-dependent motility changes in trypanosomes.Towards the biodegradation pathway of fosfomycin.Different ways to antiangiogenesis by angiostatin and suramin, and quantitation of angiostatin-induced antiangiogenesis.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Fosmidomycin for the treatment of malaria.
@ast
Fosmidomycin for the treatment of malaria.
@en
type
label
Fosmidomycin for the treatment of malaria.
@ast
Fosmidomycin for the treatment of malaria.
@en
prefLabel
Fosmidomycin for the treatment of malaria.
@ast
Fosmidomycin for the treatment of malaria.
@en
P1476
Fosmidomycin for the treatment of malaria.
@en
P2093
Hassan Jomaa
Jochen Wiesner
P2888
P356
10.1007/S00436-002-0770-9
P478
90 Suppl 2
P577
2002-11-30T00:00:00Z