A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest
about
Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4Down-regulation of Myc as a potential target for growth arrest induced by human polynucleotide phosphorylase (hPNPaseold-35) in human melanoma cellsDACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growthFOXP3 up-regulates p21 expression by site-specific inhibition of histone deacetylase 2/histone deacetylase 4 association to the locusRapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding elementA comprehensive pathway map of epidermal growth factor receptor signalingNSPc1 is a cell growth regulator that acts as a transcriptional repressor of p21Waf1/Cip1 via the RARE elementSwitching Roles of TGF-β in Cancer Development: Implications for Therapeutic Target and Biomarker StudiesMyc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoterBoth Max and TFE3 cooperate with Smad proteins to bind the plasminogen activator inhibitor-1 promoter, but they have opposite effects on transcriptional activityOncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesisThe ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functionsCell growth suppression by thanatos-associated protein 11(THAP11) is mediated by transcriptional downregulation of c-MycIntestinal cell kinase, a MAP kinase-related kinase, regulates proliferation and G1 cell cycle progression of intestinal epithelial cells.Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulationTranscriptional regulation of BRD7 expression by Sp1 and c-Myc.Division and apoptosis of E2f-deficient retinal progenitorsThe regulation of TGF-β/SMAD signaling by protein deubiquitination.Myc interacts with Max and Miz1 to repress C/EBPdelta promoter activity and gene expression.Myc-induced microRNAs integrate Myc-mediated cell proliferation and cell fate.Bifurcated converging pathways for high Ca2+- and TGFbeta-induced inhibition of growth of normal human keratinocytesThe endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3.MYC cofactors: molecular switches controlling diverse biological outcomes.Mad upregulation and Id2 repression accompany transforming growth factor (TGF)-beta-mediated epithelial cell growth suppression.1α,25-dihydroxyvitamin D3 inhibits C4-2 prostate cancer cell growth via a retinoblastoma protein (Rb)-independent G1 arrestOverexpression of c-Myc alters G(1)/S arrest following ionizing radiationTGF-beta flips the Myc switch.Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program.Functional validation of genes implicated in lymphomagenesis: an in vivo selection assay using a Myc-induced B-cell tumor.Ischemic and nephrotoxic acute renal failure are distinguished by their broad transcriptomic responses.Ras-MAP kinase signaling pathways and control of cell proliferation: relevance to cancer therapy.c-Myc is essential to prevent endothelial pro-inflammatory senescent phenotype.Berbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity.Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.Genetic instability, oncogenes, and the p53 pathway.Efficient induction of apoptosis by wee1 kinase inhibition in hepatocellular carcinoma cells.Transforming growth factor-beta signaling in normal and malignant hematopoiesis.Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.Effects of heme oxygenase-1 on induction and development of chemically induced squamous cell carcinoma in mice.
P2860
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P2860
A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
A role for transcriptional rep ...... eta -induced cell-cycle arrest
@ast
A role for transcriptional rep ...... eta -induced cell-cycle arrest
@en
type
label
A role for transcriptional rep ...... eta -induced cell-cycle arrest
@ast
A role for transcriptional rep ...... eta -induced cell-cycle arrest
@en
prefLabel
A role for transcriptional rep ...... eta -induced cell-cycle arrest
@ast
A role for transcriptional rep ...... eta -induced cell-cycle arrest
@en
P2860
P356
P1476
A role for transcriptional rep ...... eta -induced cell-cycle arrest
@en
P2093
G F Claassen
P2860
P304
P356
10.1073/PNAS.150006697
P407
P577
2000-08-01T00:00:00Z