NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses
about
Regulation of nuclear factor-κB in autoimmunityRoles of TRAF3 in T cells: many surprisesNF-κB Pathways in the Pathogenesis of Multiple Sclerosis and the Therapeutic ImplicationsControl of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathwaysHVEM signalling at mucosal barriers provides host defence against pathogenic bacteriaDeficiency of transcription factor RelB perturbs myeloid and DC development by hematopoietic-extrinsic mechanisms.T cell-intrinsic function of the noncanonical NF-κB pathway in the regulation of GM-CSF expression and experimental autoimmune encephalomyelitis pathogenesis.TRAF3 regulates homeostasis of CD8+ central memory T cells.The noncanonical NF-κB pathway.The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2.NF-κB–inducing kinase plays an essential T cell–intrinsic role in graft-versus-host disease and lethal autoimmunity in miceTargeting signaling factors for degradation, an emerging mechanism for TRAF functionsDendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cellsNIK prevents the development of hypereosinophilic syndrome-like disease in mice independent of IKKα activationThe NFκB-inducing kinase is essential for the developmental programming of skin-resident and IL-17-producing γδ T cells.Cell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responsesNon-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection.GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis.A cell-intrinsic requirement for NF-κB-inducing kinase in CD4 and CD8 T cell memory.Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice.TWEAK/Fn14 and Non-Canonical NF-kappaB Signaling in Kidney DiseaseRoles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions.Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?CD40L-Dependent Pathway Is Active at Various Stages of Rheumatoid Arthritis Disease Progression.The non-canonical NF-κB pathway in immunity and inflammation.Opposing roles for TRAF1 in the alternative versus classical NF-κB pathway in T cells.Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2.Dendritic cell activation, phagocytosis and CD69 expression on cognate T cells are suppressed by n-3 long-chain polyunsaturated fatty acids.Bacteria and their cell wall components uniformly co-activate interleukin-17-producing thymocytes.CD40 Mediates Maturation of Thymic Dendritic Cells Driven by Self-Reactive CD4+ Thymocytes and Supports Development of Natural Regulatory T Cells.Differential dependence on nuclear factor-κB-inducing kinase among natural killer T-cell subsets in their development.
P2860
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P2860
NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
NIK signaling in dendritic cel ...... cell-mediated immune responses
@ast
NIK signaling in dendritic cel ...... cell-mediated immune responses
@en
type
label
NIK signaling in dendritic cel ...... cell-mediated immune responses
@ast
NIK signaling in dendritic cel ...... cell-mediated immune responses
@en
prefLabel
NIK signaling in dendritic cel ...... cell-mediated immune responses
@ast
NIK signaling in dendritic cel ...... cell-mediated immune responses
@en
P2093
P2860
P50
P356
P1476
NIK signaling in dendritic cel ...... cell-mediated immune responses
@en
P2093
Burkhard Becher
Janin Hofmann
Marc Schmidt-Supprian
P2860
P304
P356
10.1084/JEM.20110128
P407
P577
2011-08-01T00:00:00Z