Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- mice - Wikidata - awgldk - TriplyDB

Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- mice

Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- mice

http://www.wikidata.org/entity/Q35228098

about

Reciprocal relationship between myeloid-derived suppressor cells and T cells Establishment of lal-/- myeloid lineage cell line that resembles myeloid-derived suppressive cells Rab7 GTPase controls lipid metabolic signaling in myeloid-derived suppressor cells.Myeloid-derived suppressor cells are involved in lysosomal acid lipase deficiency-induced endothelial cell dysfunctions.Gene profile of myeloid-derived suppressive cells from the bone marrow of lysosomal acid lipase knock-out mice.Activation of mTOR pathway in myeloid-derived suppressor cells stimulates cancer cell proliferation and metastasis in lal(-/-) mice Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis.Role of Myeloid-Derived Suppressor Cells in Glucocorticoid-Mediated Amelioration of FSGS.Autophagy Is Dispensable for Macrophage-Mediated Lipid Homeostasis in Adipose Tissue Critical role of PPARγ in myeloid-derived suppressor cell-stimulated cancer cell proliferation and metastasis.Deregulation of apoptotic factors Bcl-xL and Bax confers apoptotic resistance to myeloid-derived suppressor cells and contributes to their persistence in cancer.Critical role of the mTOR pathway in development and function of myeloid-derived suppressor cells in lal-/- mice.Lysosomal acid lipase in mesenchymal stem cell stimulation of tumor growth and metastasis.Negative regulation of myeloid-derived suppressor cells in cancer.Myeloid-derived suppressor cells in cancer: recent progress and prospects.Hepatocyte-Specific Expression of Human Lysosome Acid Lipase Corrects Liver Inflammation and Tumor Metastasis in lal(-/-) Mice.Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages.Lysosomal acid lipase in cancer.Lung Epithelial Cell-Specific Expression of Human Lysosomal Acid Lipase Ameliorates Lung Inflammation and Tumor Metastasis in Lipa(-/-) Mice HMGB1 promotes myeloid-derived suppressor cells and renal cell carcinoma immune escape.Metabolic reprogramming of myeloid-derived suppressive cells.Myeloid-specific expression of Stat3C results in conversion of bone marrow mesenchymal stem cells into alveolar type II epithelial cells in the lung.

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Myeloid-specific expression of human lysosomal acid lipase corrects malformation and malfunction of myeloid-derived suppressor cells in lal-/- mice

http://www.wikidata.org/entity/Q35228098

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

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Journal of Immunology

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Myeloid-specific expression of ...... uppressor cells in lal-/- mice

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P2093

Cong Yan

http://www.w3.org/2001/XMLSchema#string

Hong Du

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Peng Qu

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Reuben Kapur

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P2860

Myeloid-derived suppressor cells: linking inflammation and cancer

Myeloid-derived suppressor cells as regulators of the immune system

Lysosomal acid lipase deficiency causes respiratory inflammation and destruction in the lung

Neutral lipids and peroxisome proliferator-activated receptor-{gamma} control pulmonary gene expression and inflammation-triggered pathogenesis in lysosomal acid lipase knockout mice

Critical roles of lysosomal acid lipase in myelopoiesis.

Overexpression of dominant negative peroxisome proliferator-activated receptor-γ (PPARγ) in alveolar type II epithelial cells causes inflammation and T-cell suppression in the lung.

Matrix metalloproteinase 12 overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis.

Macrophage-specific expression of human lysosomal acid lipase corrects inflammation and pathogenic phenotypes in lal-/- mice.

MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis

Regulatory T cells and cancer.

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