Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations.
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Understanding Genotype-Phenotype Effects in Cancer via Network ApproachesInsights into cancer severity from biomolecular interaction mechanisms.Significant Prognostic Features and Patterns of Somatic TP53 Mutations in Human CancersIdentification of driver modules in pan-cancer via coordinating coverage and exclusivity.CoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer.Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study.Network perturbation by recurrent regulatory variants in cancer.Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types.MEGSA: A Powerful and Flexible Framework for Analyzing Mutual Exclusivity of Tumor Mutations.An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer.Algorithmic methods to infer the evolutionary trajectories in cancer progression.A landscape of pharmacogenomic interactions in cancer.Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.SSA-ME Detection of cancer driver genes using mutual exclusivity by small subnetwork analysis.Individualized analysis reveals CpG sites with methylation aberrations in almost all lung adenocarcinoma tissues.Computational Methods for Characterizing Cancer Mutational Heterogeneity.Synthetic lethality and cancer.Computational approaches for the identification of cancer genes and pathwaysA Direct Test of Selection in Cell Populations Using the Diversity in Gene Expression within Tumors.A weighted exact test for mutually exclusive mutations in cancer.A new correlation clustering method for cancer mutation analysis.WeSME: uncovering mutual exclusivity of cancer drivers and beyond.Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma.SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer.A novel independence test for somatic alterations in cancer shows that biology drives mutual exclusivity but chance explains most co-occurrence.BeWith: A Between-Within method to discover relationships between cancer modules via integrated analysis of mutual exclusivity, co-occurrence and functional interactionsAn individualized gene expression signature for prediction of lung adenocarcinoma metastases.Network-Based Identification of Adaptive Pathways in Evolved Ethanol-Tolerant Bacterial Populations.OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc.A comprehensive genomic meta-analysis identifies confirmatory role of OBSCN gene in breast tumorigenesis.The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery.Graph-theoretical comparison of normal and tumor networks in identifying BRCA genes.NetSig: network-based discovery from cancer genomes.Identifying mutual exclusivity across cancer genomes: computational approaches to discover genetic interaction and reveal tumor vulnerability.Genomic Analysis of Thymic Epithelial Tumors Identifies Novel Subtypes Associated with Distinct Clinical Features.Discovering potential cancer driver genes by an integrated network-based approach.Detection of driver pathways using mutated gene network in cancer.An integrated clinical and genomic information system for cancer precision medicine.Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.Extracting Fitness Relationships and Oncogenic Patterns among Driver Genes in Cancer.
P2860
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P2860
Systematic identification of cancer driving signaling pathways based on mutual exclusivity of genomic alterations.
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Systematic identification of c ...... sivity of genomic alterations.
@ast
Systematic identification of c ...... sivity of genomic alterations.
@en
type
label
Systematic identification of c ...... sivity of genomic alterations.
@ast
Systematic identification of c ...... sivity of genomic alterations.
@en
prefLabel
Systematic identification of c ...... sivity of genomic alterations.
@ast
Systematic identification of c ...... sivity of genomic alterations.
@en
P2860
P50
P1433
P1476
Systematic identification of c ...... sivity of genomic alterations.
@en
P2093
Chris Sander
Mithat Gönen
P2860
P2888
P356
10.1186/S13059-015-0612-6
P577
2015-02-26T00:00:00Z
P5875
P6179
1038605395