Three arginines in the GABAA receptor binding pocket have distinct roles in the formation and stability of agonist- versus antagonist-bound complexes
about
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepinesEpileptic encephalopathy de novo GABRB mutations impair GABAA receptor functionPrinciples of agonist recognition in Cys-loop receptorsA nonequilibrium binary elements-based kinetic model for benzodiazepine regulation of GABAA receptors.Multiple tyrosine residues at the GABA binding pocket influence surface expression and mediate kinetics of the GABAA receptorMolecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels.A role for loop G in the β1 strand in GABAA receptor activation.A 13C-detected 15N double-quantum NMR experiment to probe arginine side-chain guanidinium 15Nη chemical shifts.Loop G in the GABAA receptor α1 subunit influences gating efficacy.Binding site opening by loop C shift and chloride ion-pore interaction in the GABAA receptor model.Capturing state-dependent dynamic events of GABAA-receptors: a microscopic look into the structural and functional insights.
P2860
Q27674189-6848CFDA-6FA4-46CB-9810-4CA57C2EF6ACQ28115275-58CFC80E-1661-4098-B2DF-7C98E01486FFQ28239408-7F450AD8-66F2-4031-B2A9-B577B69A98CCQ33826782-1F8591E6-382D-4D4B-9AC7-A1746B0BB5AAQ36504014-76B96E2B-2419-40D4-ABDA-8887FC58B0AAQ39195968-34EFA3B5-F78D-4AD2-84AA-ADD28F72CFC3Q39754103-57384D4F-3736-4889-8D25-6E54D2040750Q47154001-B2ABF639-86ED-46D2-8461-807C47285F36Q47352912-767BCB20-1D6A-4F7A-A552-B2AF35DD0B38Q52097916-448461C2-62E5-4575-B60D-315A2D9CE202Q52149242-5BE07C82-FF31-40D1-BABB-C67DD4D013DD
P2860
Three arginines in the GABAA receptor binding pocket have distinct roles in the formation and stability of agonist- versus antagonist-bound complexes
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Three arginines in the GABAA r ...... sus antagonist-bound complexes
@ast
Three arginines in the GABAA r ...... sus antagonist-bound complexes
@en
type
label
Three arginines in the GABAA r ...... sus antagonist-bound complexes
@ast
Three arginines in the GABAA r ...... sus antagonist-bound complexes
@en
prefLabel
Three arginines in the GABAA r ...... sus antagonist-bound complexes
@ast
Three arginines in the GABAA r ...... sus antagonist-bound complexes
@en
P2093
P2860
P356
P1476
Three arginines in the GABAA r ...... sus antagonist-bound complexes
@en
P2093
David A Wagner
Marcel P Goldschen-Ohm
Mathew V Jones
P2860
P304
P356
10.1124/MOL.111.072033
P577
2011-07-15T00:00:00Z