Microscopic kinetics and energetics distinguish GABA(A) receptor agonists from antagonists.
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Slow GABA transient and receptor desensitization shape synaptic responses evoked by hippocampal neurogliaform cells.Catch-and-hold activation of muscle acetylcholine receptors having transmitter binding site mutationsRegulation of output spike patterns by phasic inhibition in cerebellar granule cellsFast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networksA state-dependent salt-bridge interaction exists across the β/α intersubunit interface of the GABAA receptor.Nanodomain coupling explains Ca²⁺ independence of transmitter release time course at a fast central synapse.Synaptic acidification enhances GABAA signalingActivity-dependent inhibitory synapse remodeling through gephyrin phosphorylation.Residues in the first transmembrane domain of the Caenorhabditis elegans GABA(A) receptor confer sensitivity to the neurosteroid pregnenolone sulfate.Life at the top: the transition state of AChR gating.Three arginines in the GABAA receptor binding pocket have distinct roles in the formation and stability of agonist- versus antagonist-bound complexesA tight coupling between β₂Y97 and β₂F200 of the GABA(A) receptor mediates GABA binding2-Aminoethyl methylphosphonate, a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors.Different transmitter transients underlie presynaptic cell type specificity of GABAA,slow and GABAA,fast.An integrated catch-and-hold mechanism activates nicotinic acetylcholine receptors.A deconvolution-based method with high sensitivity and temporal resolution for detection of spontaneous synaptic currents in vitro and in vivo.Multiple tyrosine residues at the GABA binding pocket influence surface expression and mediate kinetics of the GABAA receptorGABA transporters regulate a standing GABAC receptor-mediated current at a retinal presynaptic terminal.Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hippocampal area CA1Determining synaptic parameters using high-frequency activationIndividually monitoring ligand-induced changes in the structure of the GABAA receptor at benzodiazepine binding site and non-binding-site interfaces.Neuroligin-2 accelerates GABAergic synapse maturation in cerebellar granule cellsSynaptotagmin 2 Is the Fast Ca2+ Sensor at a Central Inhibitory Synapse.Neurogliaform cells and other interneurons of stratum lacunosum-moleculare gate entorhinal-hippocampal dialogue.Dynamic functions of GABA signaling during granule cell maturation.GSG1L regulates the strength of AMPA receptor-mediated synaptic transmission but not AMPA receptor kinetics in hippocampal dentate granule neurons.The kinetics of inhibition of rat recombinant heteromeric alpha1beta glycine receptors by the low-affinity antagonist SR-95531.Modes and models of GABA(A) receptor gating.A structural model of agonist binding to the alpha3beta4 neuronal nicotinic receptor.Developmental regulation of GABAergic signalling in the hippocampus of neuroligin 3 R451C knock-in mice: an animal model of AutismGABA-independent GABAA receptor openings maintain tonic currents.Activity- and age-dependent modulation of GABAergic neurotransmission by system A-mediated glutamine uptake.A spontaneous tonic chloride conductance in solitary glutamatergic hippocampal neurons.Gephyrin regulates GABAergic and glutamatergic synaptic transmission in hippocampal cell culturesEffects of glutamate and ivermectin on single glutamate-gated chloride channels of the parasitic nematode H. contortus.Antagonism of P2X3-containing channels: commentary on Spelta et al.Presynaptic and postsynaptic mechanisms underlie paired pulse depression at single GABAergic boutons in rat collicular cultures.Declusterization of GABAA receptors affects the kinetic properties of GABAergic currents in cultured hippocampal neurons.Activation-dependent properties of pregnenolone sulfate inhibition of GABAA receptor-mediated current.Synaptic Specializations Support Frequency-Independent Purkinje Cell Output from the Cerebellar Cortex.
P2860
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P2860
Microscopic kinetics and energetics distinguish GABA(A) receptor agonists from antagonists.
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Microscopic kinetics and energ ...... ptor agonists from antagonists
@nl
Microscopic kinetics and energ ...... tor agonists from antagonists.
@ast
Microscopic kinetics and energ ...... tor agonists from antagonists.
@en
type
label
Microscopic kinetics and energ ...... ptor agonists from antagonists
@nl
Microscopic kinetics and energ ...... tor agonists from antagonists.
@ast
Microscopic kinetics and energ ...... tor agonists from antagonists.
@en
prefLabel
Microscopic kinetics and energ ...... ptor agonists from antagonists
@nl
Microscopic kinetics and energ ...... tor agonists from antagonists.
@ast
Microscopic kinetics and energ ...... tor agonists from antagonists.
@en
P2093
P2860
P1433
P1476
Microscopic kinetics and energ ...... tor agonists from antagonists.
@en
P2093
P2860
P304
P356
10.1016/S0006-3495(01)75909-7
P407
P577
2001-11-01T00:00:00Z