A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.
about
Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteinsMedical immunology: a new journal for a new subspecialty.Interleukin-15 biology and its therapeutic implications in cancerIL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cellsParasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditionsGeneration of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptidesImmunotherapy of Childhood SarcomasCrystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in transNatural splicing of exon 2 of human interleukin-15 receptor alpha-chain mRNA results in a shortened form with a distinct pattern of expressionInterleukin-15 prevents mouse mast cell apoptosis through STAT6-mediated Bcl-xL expressionIdentification of an interleukin-15alpha receptor-binding site on human interleukin-15Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restrictionReversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient miceIL-15 expression on RA synovial fibroblasts promotes B cell survivalIL-15Rα deficiency in skeletal muscle alters respiratory function and the proteome of mitochondrial subpopulations independent of changes to the mitochondrial genomeRedistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer.Interleukin-15 and its receptor augment dendritic cell vaccination against the neu oncogene through the induction of antibodies partially independent of CD4 help.In vivo modulation of vaccine-induced immune responses toward a Th1 phenotype increases potency and vaccine effectiveness in a herpes simplex virus type 2 mouse model.The effects of ultraviolet radiation on the human immune system.Pathological roles of interleukin-15 in adult T-cell leukemia.In vivo regulation of replicative Legionella pneumophila lung infection by endogenous interleukin-12.Interleukin-15 augments superoxide production and microbicidal activity of human monocytes against Candida albicans.Protective roles of gamma delta T cells and interleukin-15 in Escherichia coli infection in mice.Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo.IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cellsIL-15: a central regulator of celiac disease immunopathology.Viral activation of interleukin-15 (IL-15): characterization of a virus-inducible element in the IL-15 promoter region.Interleukin-15 expression is increased in human eosinophilic esophagitis and mediates pathogenesis in mice.Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy.Having it all? Stem cells, haematopoiesis and lymphopoiesis in adult human liver.Primary human T lymphocytes engineered with a codon-optimized IL-15 gene resist cytokine withdrawal-induced apoptosis and persist long-term in the absence of exogenous cytokine.The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseasesMigration and differentiation of CD8+ T cells.IL-15R alpha expression on CD8+ T cells is dispensable for T cell memoryProduction of bioactive soluble interleukin-15 in complex with interleukin-15 receptor alpha from a conditionally-replicating oncolytic HSV-1IL-15 deficient tax mice reveal a role for IL-1α in tumor immunityIn vitro immunologic and virologic effects of interleukin 15 on peripheral blood mononuclear cells from normal donors and human immunodeficiency virus type 1-infected patients.IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice.The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cellsType 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases.
P2860
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P2860
A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
A lymphokine, provisionally de ...... hokine-activated killer cells.
@ast
A lymphokine, provisionally de ...... hokine-activated killer cells.
@en
type
label
A lymphokine, provisionally de ...... hokine-activated killer cells.
@ast
A lymphokine, provisionally de ...... hokine-activated killer cells.
@en
prefLabel
A lymphokine, provisionally de ...... hokine-activated killer cells.
@ast
A lymphokine, provisionally de ...... hokine-activated killer cells.
@en
P2093
P2860
P356
P1476
A lymphokine, provisionally de ...... hokine-activated killer cells.
@en
P2093
Bamford RN
Goldman CK
Roessler E
Waldmann TA
P2860
P304
P356
10.1073/PNAS.91.11.4935
P407
P577
1994-05-01T00:00:00Z