Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation. - Wikidata - awgldk - TriplyDB

Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation.

Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation.

http://www.wikidata.org/entity/Q35345655

about

Structural basis of coactivation of liver receptor homolog-1 by -catenin Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21 LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner.Downregulation of microRNA-30d promotes cell proliferation and invasion by targeting LRH-1 in colorectal carcinoma.Nuclear receptors connect progenitor transcription factors to cell cycle control.Nuclear receptors and pathogenesis of pancreatic cancer.Associations of NR5A2 gene polymorphisms with the clinicopathological characteristics and survival of gastric cancer.Antiproliferation activity of a small molecule repressor of liver receptor homolog 1 Tumor-suppressive function of miR-139-5p in esophageal squamous cell carcinoma.Silencing LRH-1 in colon cancer cell lines impairs proliferation and alters gene expression programs Liver receptor homolog-1 (LRH-1): a potential therapeutic target for cancer Lymphatic reprogramming by Kaposi sarcoma herpes virus promotes the oncogenic activity of the virus-encoded G-protein-coupled receptor.Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress.Structure-based discovery of antagonists of nuclear receptor LRH-1.LRH-1-dependent programming of mitochondrial glutamine processing drives liver cancer.The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival.Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells.LRH1 as a driving factor in pancreatic cancer growth Mediators of induced pluripotency and their role in cancer cells - current scientific knowledge and future perspectives.Hepatic glucose sensing and integrative pathways in the liver.Iterative use of nuclear receptor Nr5a2 regulates multiple stages of liver and pancreas development SERBP1 Is a Component of the Liver Receptor Homologue-1 Transcriptional Complex.Effect of NR5A2 inhibition on pancreatic cancer stem cell (CSC) properties and epithelial-mesenchymal transition (EMT) markers.Liver receptor homolog-1 (NR5a2) regulates CD95/Fas ligand transcription and associated T-cell effector functions.SUMO ligase PIAS1 functions as a target gene selective androgen receptor coregulator on prostate cancer cell chromatin.LRH-1 controls proliferation in breast tumor cells by regulating CDKN1A gene expression.Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation.NR5A2 discovering compounds that block tumor growth in PDAC.POD-1/TCF21 Reduces SHP Expression, Affecting LRH-1 Regulation and Cell Cycle Balance in Adrenocortical and Hepatocarcinoma Tumor Cells.Islet β-Cell Mass Preservation and Regeneration in Diabetes Mellitus: Four Factors with Potential Therapeutic Interest.Interplay among Drosophila transcription factors Ets21c, Fos and Ftz-F1 drives JNK-mediated tumor malignancy.Context-specific transcriptional regulatory network inference from global gene expression maps using double two-way t-tests.Putting GWAS to the functional test: NR5A2 and pancreatic cancer risk.LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness.Nr5a2 heterozygosity sensitises to, and cooperates with, inflammation in KRas(G12V)-driven pancreatic tumourigenesis.Association between NR5A2 and the risk of pancreatic cancer, especially among Caucasians: a meta-analysis of case-control studies.Multiple biological functions of transcription factor 21 in the development of various cancers.LRH-1 drives hepatocellular carcinoma partially through induction of c-myc and cyclin E1, and suppression of p21

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Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation.

http://www.wikidata.org/entity/Q35345655

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Nuclear receptor liver recepto ...... cell growth and proliferation.

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Nuclear receptor liver recepto ...... cell growth and proliferation.

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type

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Nuclear receptor liver recepto ...... cell growth and proliferation.

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Nuclear receptor liver recepto ...... cell growth and proliferation.

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Nuclear receptor liver recepto ...... cell growth and proliferation.

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PNAS.1112047108

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Nuclear receptor liver recepto ...... cell growth and proliferation.

@en

P2093

Cindy Benod

http://www.w3.org/2001/XMLSchema#string

Elena P Sablin

http://www.w3.org/2001/XMLSchema#string

Grace E Kim

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Maia V Vinogradova

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Natalia Jouravel

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Robert J Fletterick

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P2860

Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP

Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Inflammation and cancer

Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development

The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)

Extranuclear functions of ER impact invasive migration and metastasis by breast cancer cells

Identification of pancreatic cancer stem cells

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10.1073/PNAS.1112047108

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41

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108

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51665382

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21949357

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3193228

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