The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1 - Wikidata - awgldk - TriplyDB

The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

http://www.wikidata.org/entity/Q27652923

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DAX-1 (NR0B1) and steroidogenic factor-1 (SF-1, NR5A1) in human disease Structure of SF-1 Bound by Different Phospholipids: Evidence for Regulatory Ligands The Orphan Nuclear Receptor TR4 Is a Vitamin A-activated Nuclear Receptor Small Molecule Agonists of the Orphan Nuclear Receptors Steroidogenic Factor-1 (SF-1, NR5A1) and Liver Receptor Homologue-1 (LRH-1, NR5A2)Structural basis of coactivation of liver receptor homolog-1 by -catenin Antidiabetic phospholipid–nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation The Crystal Structure of the Orphan Nuclear Receptor NR2E3/PNR Ligand Binding Domain Reveals a Dimeric Auto-Repressed Conformation Structural insights into gene repression by the orphan nuclear receptor SHP The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable Disulfide-Trapping Identifies a New, Effective Chemical Probe for Activating the Nuclear Receptor Human LRH-1 (NR5A2)Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells Hormone binding and co-regulator binding to the glucocorticoid receptor are allosterically coupled.Orphan nuclear receptor DAX-1 acts as a novel corepressor of liver X receptor alpha and inhibits hepatic lipogenesis.Structural and functional insights into nuclear receptor signaling.Dax1 up-regulates Oct4 expression in mouse embryonic stem cells via LRH-1 and SRA.The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1.Structural basis for corepressor assembly by the orphan nuclear receptor TLX.Nuclear receptor liver receptor homologue 1 (LRH-1) regulates pancreatic cancer cell growth and proliferation.Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket.The orphan nuclear receptor DAX-1 functions as a potent corepressor of the constitutive androstane receptor (NR1I3).Rare Causes of Primary Adrenal Insufficiency: Genetic and Clinical Characterization of a Large Nationwide Cohort Emerging actions of the nuclear receptor LRH-1 in the gut.Structure-based discovery of antagonists of nuclear receptor LRH-1.Targeting DAX-1 in embryonic stem cells and cancer.The orphan nuclear receptors at their 25-year reunion.Hepatic glucose sensing and integrative pathways in the liver.Adrenocortical growth and cancer.Structure and Dynamics of the Liver Receptor Homolog 1-PGC1α Complex.E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis POD-1/TCF21 Reduces SHP Expression, Affecting LRH-1 Regulation and Cell Cycle Balance in Adrenocortical and Hepatocarcinoma Tumor Cells.Tris-nitrilotriacetic acids of subnanomolar affinity toward hexahistidine tagged molecules.Late-onset X-linked adrenal hypoplasia (DAX-1, NR0B1): two new adult-onset cases from a single center.Novel polymorphisms of nuclear receptor SHP associated with functional and structural changes Insights into the binding mode and mechanism of action of some atypical retinoids as ligands of the small heterodimer partner (SHP).Nuclear hormone receptor architecture - form and dynamics: The 2009 FASEB Summer Conference on Dynamic Structure of the Nuclear Hormone Receptors.Computational studies of LXR molecular interactions reveal an allosteric communication pathway.Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer.Decoding the Pluripotency Network: The Emergence of New Transcription Factors.Distinct nuclear receptor expression in stroma adjacent to breast tumors.The human adrenal cortex: growth control and disorders

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The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

http://www.wikidata.org/entity/Q27652923

description

2008 nî lūn-bûn

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2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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type

label

The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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prefLabel

The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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Proceedings of the National Academy of Sciences of the United States of America

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The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1

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April Woods

http://www.w3.org/2001/XMLSchema#string

Elena P Sablin

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Holly A Ingraham

http://www.w3.org/2001/XMLSchema#string

Irina N Krylova

http://www.w3.org/2001/XMLSchema#string

Peter Hwang

http://www.w3.org/2001/XMLSchema#string

Robert J Fletterick

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P2860

Inhibition of androgen receptor (AR) function by the reproductive orphan nuclear receptor DAX-1

Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity

Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP

Repressors of androgen and progesterone receptor action

DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well as DAX1-SHP heterodimers

Quantitative proteomics of the thyroid hormone receptor-coregulator interactions

CPF: an orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7alpha-hydroxylase gene

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105

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