The C terminus of talin links integrins to cell cycle progression.
about
Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamicsIntegrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesionsFAK promotes recruitment of talin to nascent adhesions to control cell motilityαV-integrins are required for mechanotransduction in MDCK epithelial cellsVinculin controls talin engagement with the actomyosin machinery.RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and TurnoverA tumor-penetrating peptide modification enhances the antitumor activity of thymosin alpha 1The extracellular matrix: a dynamic niche in cancer progressionPodocyte-associated talin1 is critical for glomerular filtration barrier maintenance.Induction of focal adhesions and motility in Drosophila S2 cellsIntegrins in development and cancer.Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.Talins and kindlins: partners in integrin-mediated adhesion.Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells.Cell adhesion-dependent serine 85 phosphorylation of paxillin modulates focal adhesion formation and haptotactic migration via association with the C-terminal tail domain of talin.Relationship between histology, development and tumorigenesis of mammary gland in female rat.An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium.Foetal bovine serum-derived exosomes affect yield and phenotype of human cardiac progenitor cell cultureCellular microenvironment controls the nuclear architecture of breast epithelia through β1-integrin.How integrins control breast biology.Talin-bound NPLY motif recruits integrin-signaling adapters to regulate cell spreading and mechanosensing.Integrin bi-directional signaling across the plasma membrane.Molecular targets in the discovery and development of novel antimetastatic agents: current progress and future prospects.Mechanisms of talin-dependent integrin signaling and crosstalkProtein conformation as a regulator of cell-matrix adhesion.Focal adhesion kinase (FAK) perspectives in mechanobiology: implications for cell behaviour.The importance of podocyte adhesion for a healthy glomerulus.Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin.Intracellular signaling of cardiac fibroblasts.GL-9 peptide regulates gene expression of CD44 cancer marker and pro-inflammatory cytokine TNF-α in human lung epithelial adenocarcinoma cell line (A549).A modified thymosin alpha 1 inhibits the growth of breast cancer both in vitro and in vivo: suppressment of cell proliferation, inducible cell apoptosis and enhancement of targeted anticancer effects.Non-monotonic cellular responses to heterogeneity in talin protein expression-level.A proteomics view on integrin-mediated adhesions.The 2016 John J. Abel Award Lecture: Targeting the Mechanical Microenvironment in Cancer.Breast tumor stroma: A driving force in the development of resistance to therapies.Understanding the role of structural integrity and differential expression of integrin profiling to identify potential therapeutic targets in breast cancer.Addressing the Functional Determinants of FAK during Ciliogenesis in Multiciliated Cells.Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent mannerAlternative mechanisms for talin to mediate integrin functionIntegrin adhesions: who's on first? What's on second? Connections between FAK and talin.
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P2860
The C terminus of talin links integrins to cell cycle progression.
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The C terminus of talin links integrins to cell cycle progression.
@ast
The C terminus of talin links integrins to cell cycle progression.
@en
type
label
The C terminus of talin links integrins to cell cycle progression.
@ast
The C terminus of talin links integrins to cell cycle progression.
@en
prefLabel
The C terminus of talin links integrins to cell cycle progression.
@ast
The C terminus of talin links integrins to cell cycle progression.
@en
P2860
P356
P1476
The C terminus of talin links integrins to cell cycle progression
@en
P2093
Charles H Streuli
Pengbo Wang
P2860
P304
P356
10.1083/JCB.201104128
P407
P577
2011-10-01T00:00:00Z