Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers.
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Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombinationMammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repairHuman SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleasesMeiotic versus mitotic recombination: two different routes for double-strand break repair: the different functions of meiotic versus mitotic DSB repair are reflected in different pathway usage and different outcomesMus81 nuclease and Sgs1 helicase are essential for meiotic recombination in a protist lacking a synaptonemal complexREC, Drosophila MCM8, drives formation of meiotic crossovers.Nucleases in homologous recombination as targets for cancer therapyMeiotic development in Caenorhabditis elegansSmc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisionsCombinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleasesJoint molecule resolution requires the redundant activities of MUS-81 and XPF-1 during Caenorhabditis elegans meiosisMammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesisCaenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediatesBLM helicase ortholog Sgs1 is a central regulator of meiotic recombination intermediate metabolismDelineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvaseThe Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repairInterplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosisThe XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.MUS81 generates a subset of MLH1-MLH3-independent crossovers in mammalian meiosis.Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates.Substrate preference of Gen endonucleases highlights the importance of branched structures as DNA damage repair intermediates.GEN1/Yen1 and the SLX4 complex: Solutions to the problem of Holliday junction resolution.Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes.Three structure-selective endonucleases are essential in the absence of BLM helicase in Drosophila.Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossoversRegulation of DNA cross-link repair by the Fanconi anemia/BRCA pathwaySLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germline.Drosophila FANCM helicase prevents spontaneous mitotic crossovers generated by the MUS81 and SLX1 nucleases.Mus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast.Increased meiotic crossovers and reduced genome stability in absence of Schizosaccharomyces pombe Rad16 (XPF).Mutational analysis of the Drosophila DNA repair and recombination gene mei-9A large-scale screen for mutagen-sensitive loci in Drosophila.Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.Unique invasions and resolutions: DNA repair proteins in meiotic recombination in Drosophila melanogaster.Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchangeSynthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis.A genetic screen for DNA double-strand break repair mutations in DrosophilaA genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint.Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structuresRegulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4.
P2860
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P248
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P2860
Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers.
description
2002 nî lūn-bûn
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2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
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name
Drosophila MUS312 interacts wi ...... o generate meiotic crossovers.
@ast
Drosophila MUS312 interacts wi ...... o generate meiotic crossovers.
@en
type
label
Drosophila MUS312 interacts wi ...... o generate meiotic crossovers.
@ast
Drosophila MUS312 interacts wi ...... o generate meiotic crossovers.
@en
prefLabel
Drosophila MUS312 interacts wi ...... o generate meiotic crossovers.
@ast
Drosophila MUS312 interacts wi ...... o generate meiotic crossovers.
@en
P2093
P2860
P1433
P1476
Drosophila MUS312 interacts wi ...... o generate meiotic crossovers.
@en
P2093
Benjamin Kramer
Jeff J Sekelsky
Ozlem Yildiz
Samarpan Majumder
P2860
P304
P356
10.1016/S1097-2765(02)00782-7
P577
2002-12-01T00:00:00Z