RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity.

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity.

Item
http://www.wikidata.org/entity/Q35512908
Redox-based therapeutics in neurodegenerative disease.Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405.The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activationPhase 1 Study of a Sulforaphane-Containing Broccoli Sprout Homogenate for Sickle Cell DiseaseNrf2--a therapeutic target for the treatment of neurodegenerative diseases.Esculetin induces antiproliferative and apoptotic response in pancreatic cancer cells by directly binding to KEAP1.Therapeutic Targeting of Cellular Stress to Prevent Cardiovascular Disease: A Review of the Evidence.Pharmacological therapeutics in Friedreich ataxia: the present state.Collaborative Power of Nrf2 and PPARγ Activators against Metabolic and Drug-Induced Oxidative InjuryA unique tolerizing dendritic cell phenotype induced by the synthetic triterpenoid CDDO-DFPA (RTA-408) is protective against EAE.Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors.Simvastatin as a Potential Disease-Modifying Therapy for Patients with Parkinson's Disease: Rationale for Clinical Trial, and Current Progress.The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the KrasG12D;Pdx1-Cre (KC) mouse model of pancreatic cancer.RTA-408 Protects Kidney from Ischemia-Reperfusion Injury in Mice via Activating Nrf2 and Downstream GSH Biosynthesis Gene.Emerging therapeutics for the treatment of Friedreich’s ataxiap62-Keap1-NRF2-ARE Pathway: A Contentious Player for Selective Targeting of Autophagy, Oxidative Stress and Mitochondrial Dysfunction in Prion Diseases
P2860

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity.

Item
http://www.wikidata.org/entity/Q35512908
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
RTA 408, A Novel Synthetic Tri ...... nd Anti-Inflammatory Activity.
@ast
RTA 408, A Novel Synthetic Tri ...... nd Anti-Inflammatory Activity.
@en
type
label
RTA 408, A Novel Synthetic Tri ...... nd Anti-Inflammatory Activity.
@ast
RTA 408, A Novel Synthetic Tri ...... nd Anti-Inflammatory Activity.
@en
prefLabel
RTA 408, A Novel Synthetic Tri ...... nd Anti-Inflammatory Activity.
@ast
RTA 408, A Novel Synthetic Tri ...... nd Anti-Inflammatory Activity.
@en
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RTA 408, A Novel Synthetic Tri ...... nd Anti-Inflammatory Activity.
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0122942
P407
P433
P478
P50
P577
P5875
P698
P932