Altered neocortical rhythmic activity states in Fmr1 KO mice are due to enhanced mGluR5 signaling and involve changes in excitatory circuitry
about
Neuropathology and animal models of autism: genetic and environmental factorsAltered Neuronal and Circuit Excitability in Fragile X Syndrome.Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia.Following the genes: a framework for animal modeling of psychiatric disordersThe contribution of inhibitory interneurons to circuit dysfunction in Fragile X SyndromeThe pathophysiology of fragile X (and what it teaches us about synapses)Channelopathies and dendritic dysfunction in fragile X syndrome.Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromesIncreased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and BackA Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model.Sensory processing in autism spectrum disorders and Fragile X syndrome-From the clinic to animal models.MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice.Degraded speech sound processing in a rat model of fragile X syndromeAuditory processing in fragile x syndrome.Investigating mechanisms underlying neurodevelopmental phenotypes of autistic and intellectual disability disorders: a perspective.Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome.Circuit level defects in the developing neocortex of Fragile X mice.Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neuronsNeural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndromeAcamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxietyCerebellar Development and Autism Spectrum Disorder in Tuberous Sclerosis Complex.mTORC1 Is a Local, Postsynaptic Voltage Sensor Regulated by Positive and Negative Feedback Pathways.Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismDeficient tonic GABAergic conductance and synaptic balance in the fragile X syndrome amygdalaGlutamate induces the elongation of early dendritic protrusions via mGluRs in wild type mice, but not in fragile X mice.Molecular Advances Leading to Treatment Implications for Fragile X Premutation CarriersActivity-dependent FMRP requirements in development of the neural circuitry of learning and memory.Deficits in tactile learning in a mouse model of fragile X syndrome.Selective role of the catalytic PI3K subunit p110β in impaired higher order cognition in fragile X syndrome.Pathological plasticity in fragile X syndrome.Elevated CaMKIIα and Hyperphosphorylation of Homer Mediate Circuit Dysfunction in a Fragile X Syndrome Mouse Model.Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autismAnalysis of Proteins That Rapidly Change Upon Mechanistic/Mammalian Target of Rapamycin Complex 1 (mTORC1) Repression Identifies Parkinson Protein 7 (PARK7) as a Novel Protein Aberrantly Expressed in Tuberous Sclerosis Complex (TSC)A target cell-specific role for presynaptic Fmr1 in regulating glutamate release onto neocortical fast-spiking inhibitory neurons.Sensory hypo-excitability in a rat model of fetal development in Fragile X Syndrome.APP Causes Hyperexcitability in Fragile X Mice.
P2860
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P2860
Altered neocortical rhythmic activity states in Fmr1 KO mice are due to enhanced mGluR5 signaling and involve changes in excitatory circuitry
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Altered neocortical rhythmic a ...... hanges in excitatory circuitry
@ast
Altered neocortical rhythmic a ...... hanges in excitatory circuitry
@en
type
label
Altered neocortical rhythmic a ...... hanges in excitatory circuitry
@ast
Altered neocortical rhythmic a ...... hanges in excitatory circuitry
@en
prefLabel
Altered neocortical rhythmic a ...... hanges in excitatory circuitry
@ast
Altered neocortical rhythmic a ...... hanges in excitatory circuitry
@en
P2093
P2860
P1476
Altered neocortical rhythmic a ...... hanges in excitatory circuitry
@en
P2093
Jay R Gibson
Kimberly M Huber
Seth A Hays
P2860
P304
14223-14234
P356
10.1523/JNEUROSCI.3157-11.2011
P407
P577
2011-10-01T00:00:00Z