Chromosome missegregation in human cells arises through specific types of kinetochore-microtubule attachment errors.
about
Different Facets of Copy Number Changes: Permanent, Transient, and AdaptiveCentrosomes, chromosome instability (CIN) and aneuploidyDNA damage associated with mitosis and cytokinesis failureBasic mechanism for biorientation of mitotic chromosomes is provided by the kinetochore geometry and indiscriminate turnover of kinetochore microtubules.Quantitative assessment of chromosome instability induced through chemical disruption of mitotic progressionReplication stress in Mammalian cells and its consequences for mitosisCDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following MitosisIdentification of genes that are essential to restrict genome duplication to once per cell divisionThe quantitative architecture of centromeric chromatinLoss of centrioles causes chromosomal instability in vertebrate somatic cells.Premature dyad separation in meiosis II is the major segregation error with maternal age in mouse oocytesTRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.Virtual finger boosts three-dimensional imaging and microsurgery as well as terabyte volume image visualization and analysisTransient endoreplication down-regulates the kinesin-14 HSET and contributes to genomic instability.Kinetochore microtubule establishment is defective in oocytes from aged miceReduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice.Rolled-up functionalized nanomembranes as three-dimensional cavities for single cell studies.The ARF tumor suppressor prevents chromosomal instability and ensures mitotic checkpoint fidelity through regulation of Aurora B.STAG2 promotes error correction in mitosis by regulating kinetochore-microtubule attachments.Integrity of the human centromere DNA repeats is protected by CENP-A, CENP-C, and CENP-T.A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cellsPartial Hepatectomy in Acetylation-Deficient BubR1 Mice Corroborates that Chromosome Missegregation Initiates Tumorigenesis.Somatic mosaicism detected by exon-targeted, high-resolution aCGH in 10,362 consecutive cases.RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.DNA Sequence-Specific Binding of CENP-B Enhances the Fidelity of Human Centromere FunctionLosing balance: the origin and impact of aneuploidy in cancerPlk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.Linking abnormal mitosis to the acquisition of DNA damageMicronucleus formation causes perpetual unilateral chromosome inheritance in mouse embryos.Aurora-A mediated histone H3 phosphorylation of threonine 118 controls condensin I and cohesin occupancy in mitosis.High rates of chromosome missegregation suppress tumor progression but do not inhibit tumor initiation.2n or not 2n: Aneuploidy, polyploidy and chromosomal instability in primary and tumor cells.HP1-Assisted Aurora B Kinase Activity Prevents Chromosome Segregation ErrorsCatastrophic nuclear envelope collapse in cancer cell micronuclei.Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation.Multi-layered cancer chromosomal instability phenotype.Adaptive Resistance to an Inhibitor of Chromosomal Instability in Human Cancer Cells.New insights into the troubles of aneuploidyAnalysis and Modeling of Chromosome Congression During Mitosis in the Chemotherapy Drug Cisplatin.Links between DNA Replication, Stem Cells and Cancer.
P2860
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P2860
Chromosome missegregation in human cells arises through specific types of kinetochore-microtubule attachment errors.
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Chromosome missegregation in h ...... microtubule attachment errors.
@ast
Chromosome missegregation in h ...... microtubule attachment errors.
@en
type
label
Chromosome missegregation in h ...... microtubule attachment errors.
@ast
Chromosome missegregation in h ...... microtubule attachment errors.
@en
prefLabel
Chromosome missegregation in h ...... microtubule attachment errors.
@ast
Chromosome missegregation in h ...... microtubule attachment errors.
@en
P2860
P356
P1476
Chromosome missegregation in h ...... microtubule attachment errors.
@en
P2093
Sarah L Thompson
P2860
P304
17974-17978
P356
10.1073/PNAS.1109720108
P407
P577
2011-10-13T00:00:00Z