Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
about
Regulation of kinetochore-microtubule attachments through homeostatic control during mitosisPlk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell linesNek2 activation of Kif24 ensures cilium disassembly during the cell cycleDynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunitDecoding Polo-like kinase 1 signaling along the kinetochore-centromere axisPolo-like kinase-1 regulates kinetochore-microtubule dynamics and spindle checkpoint silencing.The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle.Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation.Regulatory functional territory of PLK-1 and their substrates beyond mitosis.DNA damage modulates interactions between microRNAs and the 26S proteasomeCdk1 and Plk1 mediate a CLASP2 phospho-switch that stabilizes kinetochore-microtubule attachmentsMaking an effective switch at the kinetochore by phosphorylation and dephosphorylation.A double-edged sword: how oncogenes and tumor suppressor genes can contribute to chromosomal instabilityMulti-layered cancer chromosomal instability phenotype.The Microtubule-Depolymerizing Activity of a Mitotic Kinesin Protein KIF2A Drives Primary Cilia Disassembly Coupled with Cell Proliferation.Linked in: formation and regulation of microtubule attachments during chromosome segregation.The Elephant in the Room: The Role of Microtubules in Cancer.Molecular insight into the regulation and function of MCAK.Polo-like kinase 1 regulates the stability of the mitotic centromere-associated kinesin in mitosis.The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1All together now: Polo joins the kinase network controlling the spindle assembly checkpoint in Drosophila.Direct Functional Interaction of the Kinesin-13 Family Membrane Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1).Balancing the kinetochore ledger.Regulating PLK1 dynamics by Cullin3/KLHL22-mediated ubiquitylation.Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability.A bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase.Protein Complexes in the Nucleus: The Control of Chromosome Segregation.Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity.Kinase and Phosphatase Cross-Talk at the Kinetochore.
P2860
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P2860
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
@ast
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
@en
type
label
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
@ast
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
@en
prefLabel
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
@ast
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
@en
P2860
P50
P356
P1476
Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation
@en
P2093
Emily A Hood
P2860
P304
P356
10.1091/MBC.E11-12-1013
P577
2012-04-25T00:00:00Z