Effects of FXR in foam-cell formation and atherosclerosis development. - Wikidata - awgldk - TriplyDB

Effects of FXR in foam-cell formation and atherosclerosis development.

Effects of FXR in foam-cell formation and atherosclerosis development.

http://www.wikidata.org/entity/Q35546179

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Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes Fatty liver diseases, bile acids, and FXR Bile acid signaling in metabolic disease and drug therapy Deletion of mouse FXR gene disturbs multiple neurotransmitter systems and alters neurobehavior Data on gene and protein expression changes induced by apabetalone (RVX-208) in ex vivo treated human whole blood and primary hepatocytes.Farnesoid X receptor activation prevents the development of vascular calcification in ApoE-/- mice with chronic kidney disease.Conformational dynamics of human FXR-LBD ligand interactions studied by hydrogen/deuterium exchange mass spectrometry: insights into the antagonism of the hypolipidemic agent Z-guggulsterone.Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus Inhibition of collar-induced carotid atherosclerosis by recombinant apoA-I cysteine mutants in apoE-deficient mice.Deciphering the nuclear bile acid receptor FXR paradigm.Tissue-specific function of farnesoid X receptor in liver and intestine Development of a cell-based, high-throughput screening assay for cholesterol efflux using a fluorescent mimic of cholesterol.Deficiency of PXR decreases atherosclerosis in apoE-deficient mice.Walnut oil increases cholesterol efflux through inhibition of stearoyl CoA desaturase 1 in THP-1 macrophage-derived foam cells.Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease.Overexpression of steroidogenic acute regulatory protein in rat aortic endothelial cells attenuates palmitic acid-induced inflammation and reduction in nitric oxide bioavailability Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.Upregulation of decorin by FXR in vascular smooth muscle cells.Bile acids regulate cardiovascular function Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output Nuclear receptors and inflammatory diseases.Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice Farnesoid X receptor deficiency in mice leads to increased intestinal epithelial cell proliferation and tumor development Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet.FXR an emerging therapeutic target for the treatment of atherosclerosis Overexpression of mitochondrial cholesterol delivery protein, StAR, decreases intracellular lipids and inflammatory factors secretion in macrophages.Farnesoid X receptor-Acting through bile acids to treat metabolic disorders.Lipid-sensing nuclear receptors in the pathophysiology and treatment of the metabolic syndrome.Farnesoid X receptor alpha: a molecular link between bile acids and steroid signaling?Molecular biology of atherosclerosis.Bile acid receptors as targets for drug development.Do the Apoe-/- and Ldlr-/- Mice Yield the Same Insight on Atherogenesis?RalA signaling pathway as a therapeutic target in hepatocellular carcinoma (HCC).The role of bile acids in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine.Microbiota-induced obesity requires farnesoid X receptor Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice.Antiatherosclerotic effect of farnesoid X receptor.FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells.Presence of gallstones and the risk of cardiovascular diseases: The EPIC-Germany cohort study.

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P2860

Effects of FXR in foam-cell formation and atherosclerosis development.

http://www.wikidata.org/entity/Q35546179

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2006 nî lūn-bûn

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2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Effects of FXR in foam-cell formation and atherosclerosis development.

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Effects of FXR in foam-cell formation and atherosclerosis development.

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Effects of FXR in foam-cell formation and atherosclerosis development.

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Effects of FXR in foam-cell formation and atherosclerosis development.

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Effects of FXR in foam-cell formation and atherosclerosis development.

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Effects of FXR in foam-cell formation and atherosclerosis development.

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J.BBALIP.2006.09.018

P1433

Biochimica et Biophysica Acta

P1476

Effects of FXR in foam-cell formation and atherosclerosis development.

@en

P2093

Beverly J Paigen

http://www.w3.org/2001/XMLSchema#string

Bryan Brewer

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Frank J Gonzalez

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Grace L Guo

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Marcelo J A Amar

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Silvia Santamarina-Fojo

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Taro E Akiyama

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P2860

Identification of a nuclear receptor for bile acids

Bile acids: natural ligands for an orphan nuclear receptor

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime

Identification of a nuclear receptor that is activated by farnesol metabolites

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

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10.1016/J.BBALIP.2006.09.018

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6688046

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17110163

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atherosclerosis

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1751860

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