Enantioselective enzymes by computational design and in silico screening.
about
X-ray crystallographic validation of structure predictions used in computational design for protein stabilizationTuning and Switching Enantioselectivity of Asymmetric Carboligation in an Enzyme through Mutational Analysis of a Single Hot SpotConformational diversity and enantioconvergence in potato epoxide hydrolase 1Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes.Extending enzyme molecular recognition with an expanded amino acid alphabet.CADEE: Computer-Aided Directed Evolution of Enzymes.Origins of stereoselectivity in evolved ketoreductases.A receptor dependent-4D QSAR approach to predict the activity of mutated enzymes.Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin.Learning epistatic interactions from sequence-activity data to predict enantioselectivity.Rational and Semirational Protein Design.Designed Heme-Cage β-Sheet Miniproteins.Methodology Development in Directed Evolution: Exploring Options when Applying Triple-Code Saturation Mutagenesis.Different Structural Origins of the Enantioselectivity of Haloalkane Dehalogenases toward Linear β-Haloalkanes: Open-Solvated versus Occluded-Desolvated Active Sites.Computational design of variants for cephalosporin C acylase from Pseudomonas strain N176 with improved stability and activity.Biocatalysis in the Pharmaceutical Industry: The Need for Speed.Fully automatized high-throughput enzyme library screening using a robotic platform.Role of conformational dynamics in the evolution of novel enzyme function.Protein design: from computer models to artificial intelligence
P2860
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P2860
Enantioselective enzymes by computational design and in silico screening.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Enantioselective enzymes by computational design and in silico screening.
@ast
Enantioselective enzymes by computational design and in silico screening.
@en
type
label
Enantioselective enzymes by computational design and in silico screening.
@ast
Enantioselective enzymes by computational design and in silico screening.
@en
prefLabel
Enantioselective enzymes by computational design and in silico screening.
@ast
Enantioselective enzymes by computational design and in silico screening.
@en
P2093
P2860
P50
P356
P1476
Enantioselective enzymes by computational design and in silico screening.
@en
P2093
Dick B Janssen
Robert J Floor
Sinisa Bjelic
P2860
P304
P356
10.1002/ANIE.201411415
P407
P577
2015-02-04T00:00:00Z