Mutator phenotypes in human colorectal carcinoma cell lines. - Wikidata - awgldk - TriplyDB

Mutator phenotypes in human colorectal carcinoma cell lines.

Mutator phenotypes in human colorectal carcinoma cell lines.

http://www.wikidata.org/entity/Q35568305

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Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patients Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum.Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2 DNA polymerase delta is required for human mismatch repair in vitro Microsatellite instability in colorectal cancer Epigenetics as a mechanism driving polygenic clinical drug resistance Genetic reconstruction of individual colorectal tumor histories The immunogenicity of colorectal cancers with high-degree microsatellite instability Crystal structure of Δ-[Ru(bpy)2dppz]2+ bound to mismatched DNA reveals side-by-side metalloinsertion and intercalation Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines Mismatch repair and the hereditary non-polyposis colorectal cancer syndrome (HNPCC)Interactions of the DNA mismatch repair proteins MLH1 and MSH2 with c-MYC and MAX DNA mismatch repair and mutation avoidance pathways DNA replication fidelity and cancer Severe attenuation of the B cell immune response in Msh2-deficient mice DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha Colorectal adenoma and cancer divergence. Evidence of multilineage progression An unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency.A monofunctional platinum complex coordinated to a rhodium metalloinsertor selectively binds mismatched DNA in the minor groove.Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coli A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in genomic instability.MicroRNA-26a regulates glucose metabolism by direct targeting PDHX in colorectal cancer cells.Mutated gene-specific phenotypes of dinucleotide repeat instability in human colorectal carcinoma cell lines deficient in DNA mismatch repair.High DNA methylation pattern intratumoral diversity implies weak selection in many human colorectal cancers.Genetic analysis of mouse embryonic stem cells bearing Msh3 and Msh2 single and compound mutations Direct selection for mutators in Escherichia coli.Amplification of mutator cells in a population as a result of horizontal transfer.The protective role of symmetric stem cell division on the accumulation of heritable damage Somatic stem cells and the kinetics of mutagenesis and carcinogenesis.Mismatch repair in correction of replication errors and processing of DNA damage.A molecular rationale for the how, when and why of colorectal cancer screening.Talking tumours: histories from sequences Adaptive mutations in Escherichia coli as a model for the multiple mutational origins of tumors.DNA mismatch repair and oxidative DNA damage: implications for cancer biology and treatment.Passenger mutations as a marker of clonal cell lineages in emerging neoplasia The mutation rate and cancer.The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators.

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P2860

Mutator phenotypes in human colorectal carcinoma cell lines.

http://www.wikidata.org/entity/Q35568305

description

1994 nî lūn-bûn

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1994年の論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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1994年論文

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1994年论文

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1994年论文

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1994年论文

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name

Mutator phenotypes in human colorectal carcinoma cell lines.

@ast

Mutator phenotypes in human colorectal carcinoma cell lines.

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type

label

Mutator phenotypes in human colorectal carcinoma cell lines.

@ast

Mutator phenotypes in human colorectal carcinoma cell lines.

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prefLabel

Mutator phenotypes in human colorectal carcinoma cell lines.

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Mutator phenotypes in human colorectal carcinoma cell lines.

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PNAS.91.14.6319

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Proceedings of the National Academy of Sciences of the United States of America

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Mutator phenotypes in human colorectal carcinoma cell lines.

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Bhattacharyya NP

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Ganesh A

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Groden J

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Meuth M

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Skandalis A

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P2860

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Mutator phenotype of Werner syndrome is characterized by extensive deletions

Identification of 17 independent mutations responsible for human hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency

A genetic model for colorectal tumorigenesis

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

Microsatellite instability in cancer of the proximal colon

Mechanisms of mutagenesis in the Escherichia coli mutator mutD5: role of DNA mismatch repair.

Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells.

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6319-6323

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