Games played by rogue proteins in prion disorders and Alzheimer's disease.
about
Amyloid beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS developmentHomo- and heterodimerization of APP family members promotes intercellular adhesion.Electron microscopic structure of purified, active gamma-secretase reveals an aqueous intramembrane chamber and two pores.Unraveling prion strains with cell biology and organic chemistryBrain immune interactions and air pollution: macrophage inhibitory factor (MIF), prion cellular protein (PrP(C)), Interleukin-6 (IL-6), interleukin 1 receptor antagonist (IL-1Ra), and interleukin-2 (IL-2) in cerebrospinal fluid and MIF in serum diffObservation of spatial propagation of amyloid assembly from single nucleiDynamics of protein aggregation and oligomer formation governed by secondary nucleation.Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases.Proteomic profiling of urine identifies specific fragments of SERPINA1 and albumin as biomarkers of preeclampsia.Functionally relevant domains of the prion protein identified in vivoRepetitive immunization enhances the susceptibility of mice to peripherally administered prions.Context dependent neuroprotective properties of prion protein (PrP).Structural typing of systemic amyloidoses by luminescent-conjugated polymer spectroscopy.Cellular prion protein mediates the toxicity of beta-amyloid oligomers: implications for Alzheimer disease.Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptidesTransmembrane glycine zippers: physiological and pathological roles in membrane proteins.Thermal and sodium dodecylsulfate induced transitions of streptavidinProliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism.A common BACE1 polymorphism is a risk factor for sporadic Creutzfeldt-Jakob diseaseMissense meanderings in sequence space: a biophysical view of protein evolution.Selective re-routing of prion protein to proteasomes and alteration of its vesicular secretion prevent PrP(Sc) formation.The role of the NADPH oxidase NOX2 in prion pathogenesis.Relationship between prion propensity and the rates of individual molecular steps of fibril assembly.Molecular origin of Gerstmann-Sträussler-Scheinker syndrome: insight from computer simulation of an amyloidogenic prion peptide.Role of pharmacoproteomics in the development of personalized medicine.Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril massAntiprion immunotherapy: to suppress or to stimulate?TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.Genetic variability of the gene cluster CALHM 1-3 in sporadic Creutzfeldt-Jakob disease.Lack of association of the M129V polymorphism of the PRNP gene with pseudoexfoliation syndrome.Superresolution imaging of amyloid fibrils with binding-activated probesIntraneuronal Amylin Deposition, Peroxidative Membrane Injury and Increased IL-1β Synthesis in Brains of Alzheimer's Disease Patients with Type-2 Diabetes and in Diabetic HIP Rats.The prion protein knockout mouse: a phenotype under challenge.Chemical and biophysical insights into the propagation of prion strains.Neprilysin and Aβ Clearance: Impact of the APP Intracellular Domain in NEP Regulation and Implications in Alzheimer's DiseaseBiosensor-based label-free assays of amyloid growth.Cells and prions: a license to replicate.Protection from cytosolic prion protein toxicity by modulation of protein translocation.Autophagy flux induced by ginsenoside-Rg3 attenuates human prion protein-mediated neurotoxicity and mitochondrial dysfunction.The nature of amyloid-like glucagon fibrils
P2860
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P2860
Games played by rogue proteins in prion disorders and Alzheimer's disease.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Games played by rogue proteins in prion disorders and Alzheimer's disease.
@ast
Games played by rogue proteins in prion disorders and Alzheimer's disease.
@en
type
label
Games played by rogue proteins in prion disorders and Alzheimer's disease.
@ast
Games played by rogue proteins in prion disorders and Alzheimer's disease.
@en
prefLabel
Games played by rogue proteins in prion disorders and Alzheimer's disease.
@ast
Games played by rogue proteins in prion disorders and Alzheimer's disease.
@en
P356
P1433
P1476
Games played by rogue proteins in prion disorders and Alzheimer's disease.
@en
P304
P356
10.1126/SCIENCE.1087348
P407
P577
2003-10-01T00:00:00Z