Tubulin and microtubules as targets for anticancer drugs.
about
Spindle poisons and cell fate: a tale of two pathways.PMA synergistically enhances apicularen A-induced cytotoxicity by disrupting microtubule networks in HeLa cells.Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.Antitumor peptides from marine organismsInvestigating citrullinated proteins in tumour cell linesLipid vesicles containing transferrin receptor binding peptide TfR-T12 and octa-arginine conjugate stearyl-R8 efficiently treat brain glioma along with glioma stem cellsN-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)arylamide as a new scaffold that provides rapid access to antimicrotubule agents: synthesis and evaluation of antiproliferative activity against select cancer cell lines.Novel microtubule-targeted agent 6-chloro-4-(methoxyphenyl) coumarin induces G2-M arrest and apoptosis in HeLa cells.Synthesis and antitumor activity of 1,5-disubstituted 1,2,4-triazoles as cis-restricted combretastatin analogues.Substituted 2-(3',4',5'-trimethoxybenzoyl)-benzo[b]thiophene derivatives as potent tubulin polymerization inhibitors.Novel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluationBiological activity of 4-substituted methoxybenzoyl-aryl-thiazole: an active microtubule inhibitorDesign, Synthesis and Cytotoxicity Evaluationof New 1,2-diaryl-4, 5, 6, 7-Tetrahydro-1H-benzo[d] Imidazolesas Tubulin Inhibitors.Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-aryl/arylaminobenzo[b]thiophene derivatives as a novel class of antiproliferative agents.4-Amino-5-benzoyl-2-(4-methoxyphenylamino)thiazole (DAT1): a cytotoxic agent towards cancer cells and a probe for tubulin-microtubule system.Drugs that target dynamic microtubules: a new molecular perspectiveMG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells.Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.Methylferulate from Tamarix aucheriana inhibits growth and enhances chemosensitivity of human colorectal cancer cells: possible mechanism of action.Synthesis and biological evaluation of novel 4,5-disubstituted 2H-1,2,3-triazoles as cis-constrained analogues of combretastatin A-4Microtubule inhibitor, SP-6-27 inhibits angiogenesis and induces apoptosis in ovarian cancer cells.One-pot synthesis and in-vitro anticancer evaluation of 5-(2'-indolyl)thiazolesCytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors.SYNTHESIS AND BIOLOGICAL ACTIVITY OF SULFUR COMPOUNDS SHOWING STRUCTURAL ANALOGY WITH COMBRETASTATIN A-4.Molecular modelling, synthesis, cytotoxicity and anti-tumour mechanisms of 2-aryl-6-substituted quinazolinones as dual-targeted anti-cancer agents.Mitosis-targeted anti-cancer therapies: where they stand.Novel quinolone chalcones targeting colchicine-binding pocket kill multidrug-resistant cancer cells by inhibiting tubulin activity and MRP1 function.Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics.Phenethyl isothiocyanate induces cell cycle arrest and reduction of alpha- and beta-tubulin isotypes in human prostate cancer cells.The colchicine derivative CT20126 shows a novel microtubule-modulating activity with apoptosis.Identification of 7-(4'-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cellsMicrotubule-Actin Crosslinking Factor 1 and Plakins as Therapeutic Drug Targets.
P2860
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P2860
Tubulin and microtubules as targets for anticancer drugs.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Tubulin and microtubules as targets for anticancer drugs.
@ast
Tubulin and microtubules as targets for anticancer drugs.
@en
type
label
Tubulin and microtubules as targets for anticancer drugs.
@ast
Tubulin and microtubules as targets for anticancer drugs.
@en
prefLabel
Tubulin and microtubules as targets for anticancer drugs.
@ast
Tubulin and microtubules as targets for anticancer drugs.
@en
P2093
P1476
Tubulin and microtubules as targets for anticancer drugs
@en
P2093
Alan T McGown
John A Hadfield
Nicholas Hirst
Sylvie Ducki
P304
P577
2003-01-01T00:00:00Z