Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors. - Wikidata - awgldk - TriplyDB

Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.

Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.

http://www.wikidata.org/entity/Q35668980

about

Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones.Optimisation of tetrahydroisoquinoline-based chimeric microtubule disruptors.In-vitro Antiproliferative Activity of New Tetrahydroisoquinolines (THIQs) on Ishikawa Cells and their 3D Pharmacophore Models.Synthesis and Pharmacological Evolution of Tetrahydroisoquinolines as Anti Breast Cancer Agents.EDL-360: A Potential Novel Antiglioma Agent.Tetrahydroisoquinolinone-based steroidomimetic and chimeric microtubule disruptors.Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.Sulfatase inhibitors: a patent review.Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines.Biology-oriented synthesis of a tetrahydroisoquinoline-based compound collection targeting microtubule polymerization.Accessing simply-substituted 4-hydroxytetrahydroisoquinolines via Pomeranz-Fritsch-Bobbitt reaction with non-activated and moderately-activated systems.Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures.Synthesis and Biological Evaluations of Ring Substituted Tetrahydroisoquinolines (THIQs) as Anti-Breast Cancer Agents.Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines.

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Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.

http://www.wikidata.org/entity/Q35668980

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.

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Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.

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Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.

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ACS Medicinal Chemistry Letters

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Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors.

@en

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Barry V L Potter

http://www.w3.org/2001/XMLSchema#string

Eric Ferrandis

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Ernest Hamel

http://www.w3.org/2001/XMLSchema#string

Fabrice Jourdan

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Mark P Thomas

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Mathew P Leese

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Meriel R Kimberley

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Ruoli Bai

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Wolfgang Dohle

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P2860

2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity

Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents

Chimeric microtubule disruptors

Microtubules as a target for anticancer drugs

Steroid sulfatase: molecular biology, regulation, and inhibition.

Tubulin and microtubules as targets for anticancer drugs.

Pharmacokinetics and efficacy of 2-methoxyoestradiol and 2-methoxyoestradiol-bis-sulphamate in vivo in rodents.

Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.

Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates: synthesis, in vitro evaluation and computational modelling.

3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.

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5-9

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scholarly article

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10.1021/ML200232C

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1

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3

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2011-10-31T00:00:00Z

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221750030

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22247790

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