Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102
about
Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expressionContrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vesselsThe Foxc2 transcription factor regulates tumor angiogenesisTumor refractoriness to anti-VEGF therapyAptamers: A promising chemical antibody for cancer therapyAnti-angiogenic alternatives to VEGF blockadeEndothelial cell-pericyte interactions stimulate basement membrane matrix assembly: influence on vascular tube remodeling, maturation, and stabilizationSignaling pathways in the development of infantile hemangiomaA role for a CXCR2/phosphatidylinositol 3-kinase gamma signaling axis in acute and chronic vascular permeability.DNA Aptamer Technology for Personalized Medicine.Targeting PDGF signaling in carcinoma-associated fibroblasts controls cervical cancer in mouse modelAptamers: from bench side research towards patented molecules with therapeutic applications.Angiopoietin-2 interferes with anti-VEGFR2-induced vessel normalization and survival benefit in mice bearing gliomas.Molecular mediators of angiogenesis.Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy.Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer.Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth.Dual role of pericyte α6β1-integrin in tumour blood vessels.Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-BSDF-1α induces PDGF-B expression and the differentiation of bone marrow cells into pericytesThe antiangiogenic 16K prolactin impairs functional tumor neovascularization by inhibiting vessel maturation.Cytosolic phospholipase A2 and lysophospholipids in tumor angiogenesisMicrofluidic approaches to rapid and efficient aptamer selection.Targeting the PDGF signaling pathway in tumor treatmentA Phase II study of pulse dose imatinib mesylate and weekly paclitaxel in patients aged 70 and over with advanced non-small cell lung cancer.Fibronectins in vascular morphogenesisBlocking SDF-1α/CXCR4 downregulates PDGF-B and inhibits bone marrow-derived pericyte differentiation and tumor vascular expansion in Ewing tumors.Pericyte requirement for anti-leak action of angiopoietin-1 and vascular remodeling in sustained inflammationTargeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2.Targeting pericytes with a PDGF-B aptamer in human ovarian carcinoma models.Pericytes contribute to airway remodeling in a mouse model of chronic allergic asthmaThe role of blood vessels, endothelial cells, and vascular pericytes in insulin secretion and peripheral insulin action.Expression of FOXC2 in renal cell carcinoma and its relationship to clinical pathological featuresRole of bone marrow-derived cells in angiogenesis: focus on macrophages and pericytes.Soluble receptor-mediated selective inhibition of VEGFR and PDGFRbeta signaling during physiologic and tumor angiogenesis.An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization.Development and characterization of a high-throughput in vitro cord formation model insensitive to VEGF inhibition.Multivalent proteoglycan modulation of FGF mitogenic responses in perivascular cells.Clinicopathological significance of platelet-derived growth factor B, platelet-derived growth factor receptor-β, and E-cadherin expression in gastric carcinoma.Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes.
P2860
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P2860
Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Sequential loss of tumor vesse ...... r B by selective aptamer AX102
@ast
Sequential loss of tumor vesse ...... r B by selective aptamer AX102
@en
type
label
Sequential loss of tumor vesse ...... r B by selective aptamer AX102
@ast
Sequential loss of tumor vesse ...... r B by selective aptamer AX102
@en
prefLabel
Sequential loss of tumor vesse ...... r B by selective aptamer AX102
@ast
Sequential loss of tumor vesse ...... r B by selective aptamer AX102
@en
P2093
P2860
P1433
P1476
Sequential loss of tumor vesse ...... r B by selective aptamer AX102
@en
P2093
Amy Haskell
Barbara Sennino
Beverly L Falcón
David M Epstein
Dilara McCauley
Donald M McDonald
Jeffrey C Kurz
Thomas McCauley
P2860
P304
P356
10.1158/0008-5472.CAN-07-0293
P407
P577
2007-08-01T00:00:00Z